ID   POC5_XENLA              Reviewed;         572 AA.
AC   Q6DFB7;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=Centrosomal protein POC5;
DE   AltName: Full=Protein of centriole 5;
GN   Name=poc5;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Oocyte;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential for the assembly of the distal half of centrioles,
CC       required for centriole elongation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome, centriole {ECO:0000250}. Note=Localized to the
CC       distal portion of centrioles. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the POC5 family. {ECO:0000305}.
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DR   EMBL; BC076822; AAH76822.1; -; mRNA.
DR   RefSeq; NP_001086572.1; NM_001093103.1.
DR   AlphaFoldDB; Q6DFB7; -.
DR   SMR; Q6DFB7; -.
DR   DNASU; 446407; -.
DR   GeneID; 446407; -.
DR   KEGG; xla:446407; -.
DR   CTD; 446407; -.
DR   Xenbase; XB-GENE-5850643; poc5.L.
DR   OrthoDB; 1217267at2759; -.
DR   Proteomes; UP000186698; Chromosome 1L.
DR   Bgee; 446407; Expressed in egg cell and 19 other tissues.
DR   GO; GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   InterPro; IPR033351; POC5.
DR   PANTHER; PTHR28618; PTHR28618; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Coiled coil; Cytoplasm; Cytoskeleton; Reference proteome;
KW   Repeat.
FT   CHAIN           1..572
FT                   /note="Centrosomal protein POC5"
FT                   /id="PRO_0000281912"
FT   REPEAT          143..174
FT                   /note="Centrin-binding (CBR) 1"
FT   REPEAT          232..263
FT                   /note="Centrin-binding (CBR) 2"
FT   REPEAT          264..296
FT                   /note="Centrin-binding (CBR) 3"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          44..111
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          375..419
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          542..572
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          187..251
FT                   /evidence="ECO:0000255"
FT   COILED          317..353
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..15
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        68..99
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        378..392
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        393..419
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        542..562
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   572 AA;  63872 MW;  78FA4020E67059C8 CRC64;
     MSSDEEYRES PILPKDSDHG SSVSSDLQDE YDELLRYAVV TPRFGPHFPE QNQLFTEQIK
     SDRFSSPKDP VQEQSLARNY SEENIPECSA TSTSQRRSPP TANEEERAMS EKKSFLSGLE
     AFSPLHSEDL SLGGSTSSGS QVQQVRVKEL PVPAENMDKV EDVLDLWSGT LKTNVMAELS
     KWRLTVIEQH KLEIKNQNEK HAEQISQLSS QIDKLQDHLQ TYETSIQRKD EVISNLTHAL
     EKHKEKMELM RTFTHWRLQL TEAREEDYAR SLADRHYRNT LMKNAWKAWH SVIQSNWKDK
     IEQACRARAE EVCIELSNDY ESKLTQLNSA LGEARAEVQR LLAERGQFEG SMKKAFMRGV
     CALNMEAMSM FQGRESRMEY DPPPRREERD PSPSVTFQNP PVTSTHTSST QHELQSALHS
     PVTCEPNYIH AFGPSTVSQS KEEAGAPAVI SAATSASSVL STQKLPMPRV VTSCQQKAGK
     IITARISARP DVSQRSSKIG SNITSMAVSP PISSIVVEKH HPVTQQTISQ AAAAKYPRSA
     LQSANSVGGR STGQSGRVSQ SHAGIHSIKV VD