POF13_SCHPO
ID POF13_SCHPO Reviewed; 396 AA.
AC O94334;
DT 27-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 110.
DE RecName: Full=F-box protein pof13;
GN Name=pof13; ORFNames=SPBC1271.01c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Harrison C.L., Toda T.;
RT "Systematic genome-wide analysis of F-box protein-encoding genes in fission
RT yeast.";
RL Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [3]
RP INTERACTION WITH SKP1.
RX PubMed=15147268; DOI=10.1111/j.1356-9597.2004.00730.x;
RA Lehmann A., Katayama S., Harrison C., Dhut S., Kitamura K., McDonald N.,
RA Toda T.;
RT "Molecular interactions of fission yeast Skp1 and its role in the DNA
RT damage checkpoint.";
RL Genes Cells 9:367-382(2004).
RN [4]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- SUBUNIT: Part of a SCF (SKP1-cullin-F-box) protein ligase complex (By
CC similarity). Interacts with skp1. {ECO:0000250,
CC ECO:0000269|PubMed:15147268}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
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DR EMBL; AB062275; BAB55892.1; -; Genomic_DNA.
DR EMBL; CU329671; CAA22191.1; -; Genomic_DNA.
DR PIR; T39337; T39337.
DR RefSeq; NP_595149.1; NM_001021057.2.
DR AlphaFoldDB; O94334; -.
DR BioGRID; 276720; 24.
DR IntAct; O94334; 1.
DR STRING; 4896.SPBC1271.01c.1; -.
DR PaxDb; O94334; -.
DR EnsemblFungi; SPBC1271.01c.1; SPBC1271.01c.1:pep; SPBC1271.01c.
DR GeneID; 2540187; -.
DR KEGG; spo:SPBC1271.01c; -.
DR PomBase; SPBC1271.01c; pof13.
DR VEuPathDB; FungiDB:SPBC1271.01c; -.
DR HOGENOM; CLU_685421_0_0_1; -.
DR OMA; PLNACKI; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:O94334; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0000151; C:ubiquitin ligase complex; ISM:PomBase.
DR GO; GO:0030674; F:protein-macromolecule adaptor activity; ISM:PomBase.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:PomBase.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR SUPFAM; SSF81383; SSF81383; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Reference proteome; Ubl conjugation pathway.
FT CHAIN 1..396
FT /note="F-box protein pof13"
FT /id="PRO_0000119978"
FT DOMAIN 40..89
FT /note="F-box"
SQ SEQUENCE 396 AA; 45451 MW; D3F7C905B584C1E6 CRC64;
MRPTHWSSNQ CEVDFTAEAL TTLSLSNRNH EEDPIQPVLK NSNLFLLNRD IWSLIINYLD
AFDILRLMHS SRQFYYWLRK SAVDECCFNN NFLNLQPYQR TVPVASDLEW ATEVDLYGNP
PILKLQLRDS FVWSMLAKFQ GLQTIALDGT GVTISSVTNI LLNIPTVKTL SIRWCVGVCS
LSLIEFLQNS KSRTFSLENL YVLGVKGLEL LKPVLLDGSE DDTLTSNWHS RVILFQNALD
ALPTTHGNPV ECDISRCPLN ACKIAGQETE LADLFSLQKV PACIYCLREW KKPICRYCID
LRSCLVCDSF VCPSCISLDF DLQIQAFARQ HRVISTLGVV YPEREDSCFH KIKAAQWHQI
SPRSLLFQFQ EQNHIHHKKI RRKLLAAGWK WPQSQI
