POF7_SCHPO
ID POF7_SCHPO Reviewed; 361 AA.
AC O74531; Q9USL9;
DT 06-DEC-2002, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2002, sequence version 2.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=F-box protein pof7;
GN Name=pof7; ORFNames=SPCC1827.08c, SPCC70.11c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 6-361.
RA Harrison C.L., Toda T.;
RT "Systematic genome-wide analysis of F-box protein-encoding genes in fission
RT yeast.";
RL Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP INTERACTION WITH SKP1.
RX PubMed=15147268; DOI=10.1111/j.1356-9597.2004.00730.x;
RA Lehmann A., Katayama S., Harrison C., Dhut S., Kitamura K., McDonald N.,
RA Toda T.;
RT "Molecular interactions of fission yeast Skp1 and its role in the DNA
RT damage checkpoint.";
RL Genes Cells 9:367-382(2004).
RN [4]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBUNIT: Interacts with skp1. {ECO:0000269|PubMed:15147268}.
CC -!- INTERACTION:
CC O74531; Q9Y709: skp1; NbExp=2; IntAct=EBI-1185549, EBI-1172248;
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329672; CAA19361.1; -; Genomic_DNA.
DR EMBL; AB062776; BAB60687.1; -; Genomic_DNA.
DR PIR; T41557; T41557.
DR RefSeq; NP_588546.2; NM_001023533.2.
DR AlphaFoldDB; O74531; -.
DR SMR; O74531; -.
DR BioGRID; 275714; 21.
DR IntAct; O74531; 1.
DR MINT; O74531; -.
DR STRING; 4896.SPCC1827.08c.1; -.
DR MaxQB; O74531; -.
DR PaxDb; O74531; -.
DR EnsemblFungi; SPCC1827.08c.1; SPCC1827.08c.1:pep; SPCC1827.08c.
DR GeneID; 2539142; -.
DR KEGG; spo:SPCC1827.08c; -.
DR PomBase; SPCC1827.08c; pof7.
DR VEuPathDB; FungiDB:SPCC1827.08c; -.
DR eggNOG; KOG2997; Eukaryota.
DR HOGENOM; CLU_017706_1_0_1; -.
DR InParanoid; O74531; -.
DR OMA; DEFRENW; -.
DR PhylomeDB; O74531; -.
DR Reactome; R-SPO-8951664; Neddylation.
DR Reactome; R-SPO-983168; Antigen processing: Ubiquitination & Proteasome degradation.
DR PRO; PR:O74531; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0019005; C:SCF ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0030674; F:protein-macromolecule adaptor activity; ISM:PomBase.
DR GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR045118; FBXO9/FBXO48.
DR InterPro; IPR045464; Hrt3/FBXO9_C.
DR PANTHER; PTHR12874; PTHR12874; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF19270; FBO_C; 1.
DR SUPFAM; SSF81383; SSF81383; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Reference proteome; Ubl conjugation pathway.
FT CHAIN 1..361
FT /note="F-box protein pof7"
FT /id="PRO_0000119974"
FT DOMAIN 105..157
FT /note="F-box"
SQ SEQUENCE 361 AA; 41933 MW; 0269BAE9AEDEB5B5 CRC64;
MSTVEDQLSL ELETVNKDIL LKKALLHYKD AIKSEREGNL GESLNKYRLA HKVHEDVESI
YRRLERLQLC KRNEEEEMLN SDASEAMLTV SSVPSPTLTE NESVNESVVP NILKLPDEVL
LVILENCIRD LHDLRYLSSI ALTCKHFAKA LRADSLYRSF CYCSCEQKEW QQSIKSIEEE
LVEKYQQSWK TLFLKKPRSR FDGCYISVCR YFRPGTSDTS WNQPIHLITY YRYLRLYPNS
TCIVYQSSNE PNDVVRNFSV QNTSLFSPMS SSPMFSNGNV ALTGSWSMTP SGEMLIVYPA
SQTYTYVQKL QVRGIRLKWI SFYSIHNYTS FTNEMPLTHN RDYVFSRVYS YTADSESLKR
G
