ID   POF9_SCHPO              Reviewed;         467 AA.
AC   O74381;
DT   27-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   03-AUG-2022, entry version 133.
DE   RecName: Full=F-box protein pof9;
GN   Name=pof9; ORFNames=SPBC3H7.06c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Harrison C.L., Toda T.;
RT   "Systematic genome-wide analysis of F-box protein-encoding genes in fission
RT   yeast.";
RL   Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [3]
RP   INTERACTION WITH SKP1.
RX   PubMed=15147268; DOI=10.1111/j.1356-9597.2004.00730.x;
RA   Lehmann A., Katayama S., Harrison C., Dhut S., Kitamura K., McDonald N.,
RA   Toda T.;
RT   "Molecular interactions of fission yeast Skp1 and its role in the DNA
RT   damage checkpoint.";
RL   Genes Cells 9:367-382(2004).
RN   [4]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBUNIT: Interacts with skp1. {ECO:0000269|PubMed:15147268}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}.
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DR   EMBL; AB061727; BAB55638.1; -; Genomic_DNA.
DR   EMBL; CU329671; CAA20302.1; -; Genomic_DNA.
DR   PIR; T40409; T40409.
DR   RefSeq; NP_595769.1; NM_001021670.1.
DR   AlphaFoldDB; O74381; -.
DR   SMR; O74381; -.
DR   BioGRID; 277513; 96.
DR   IntAct; O74381; 1.
DR   STRING; 4896.SPBC3H7.06c.1; -.
DR   MaxQB; O74381; -.
DR   PaxDb; O74381; -.
DR   EnsemblFungi; SPBC3H7.06c.1; SPBC3H7.06c.1:pep; SPBC3H7.06c.
DR   GeneID; 2540997; -.
DR   KEGG; spo:SPBC3H7.06c; -.
DR   PomBase; SPBC3H7.06c; pof9.
DR   VEuPathDB; FungiDB:SPBC3H7.06c; -.
DR   eggNOG; ENOG502QUVE; Eukaryota.
DR   HOGENOM; CLU_585471_0_0_1; -.
DR   InParanoid; O74381; -.
DR   OMA; QSAMMAI; -.
DR   PhylomeDB; O74381; -.
DR   PRO; PR:O74381; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0000151; C:ubiquitin ligase complex; ISM:PomBase.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:GO_Central.
DR   GO; GO:0030674; F:protein-macromolecule adaptor activity; ISM:PomBase.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:PomBase.
DR   Gene3D; 2.130.10.30; -; 2.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR009091; RCC1/BLIP-II.
DR   InterPro; IPR000408; Reg_chr_condens.
DR   Pfam; PF00646; F-box; 1.
DR   SMART; SM00256; FBOX; 1.
DR   SUPFAM; SSF50985; SSF50985; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
DR   PROSITE; PS50181; FBOX; 1.
DR   PROSITE; PS50012; RCC1_3; 2.
PE   1: Evidence at protein level;
KW   Cytoplasm; Nucleus; Reference proteome; Repeat; Ubl conjugation pathway.
FT   CHAIN           1..467
FT                   /note="F-box protein pof9"
FT                   /id="PRO_0000119976"
FT   DOMAIN          3..49
FT                   /note="F-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT   REPEAT          77..131
FT                   /note="RCC1 1"
FT   REPEAT          302..354
FT                   /note="RCC1 2"
FT   REPEAT          355..417
FT                   /note="RCC1 3"
SQ   SEQUENCE   467 AA;  52419 MW;  154909F3C9C3E6EB CRC64;
     MAKSPFLELS YDILLEISTY LDYKDIVHLS ETCKSLSYVF DDKTIWHRFC ARVQGLTNVV
     PVVDDNYKRP YAVWKDRGYA YSWGQQIRNY LGRVVNTNQY PRDRPGALTG KDVRSTIQVQ
     VGGYGMYLLN ENGNLYVTGV PNNVGPELMR DLEPIVKIHA GREFCLALGE TGHLYQVSLK
     TRICLTDEQN MLSAYRGRIA NFKSGWDSHS AYVPGIGFLV WHTGRESEAQ LFQPEASMKE
     FVLNDYVHCA GFLVYTVASP QKKGAVFRLD LDQATQHTLG RELKRFASHD PHQGWHLAGS
     FETFTCLSDD GNTVYMGHAN TKQVDDDPVI HDFLQNRGIK QLAHGDHHHL YLTSDHSIWS
     WGVELRYCGC LGLGSLHLQE QTSDPSIVSD PRTARNIVSI PHQIHFSGTC YSVAAGGWQS
     AALAISESVL PEVNVPPITT FSIIRPSRVP ALRFLAAPAT RTLERDG