ID   POG1_YEAS7              Reviewed;         351 AA.
AC   A6ZVF4;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   03-AUG-2022, entry version 43.
DE   RecName: Full=Transcriptional activator POG1;
DE   AltName: Full=Promoter of growth protein 1;
GN   Name=POG1; ORFNames=SCY_2670;
OS   Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=307796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJM789;
RX   PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA   Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA   Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA   Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA   Steinmetz L.M.;
RT   "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT   strain YJM789.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC   -!- FUNCTION: Transcriptional activator which promotes cell cycle recovery
CC       with CLN2, after pheromone induced G1 arrest, probably inhibiting the
CC       ability of STE20 to activate the pheromone response pathway. Binds the
CC       promoters of genes that function in cell cycle regulation, cytoskeletal
CC       organization, and spindle assembly. May also be involved in stress-
CC       resistance (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- INDUCTION: Expressed periodically during cell division. Regulated by
CC       the SBF complex which is one critical regulator of the start of the
CC       cell cycle (By similarity). {ECO:0000250}.
CC   -!- PTM: Phosphorylated by CDC28. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the POG1 family. {ECO:0000305}.
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DR   EMBL; AAFW02000124; EDN61379.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6ZVF4; -.
DR   PRIDE; A6ZVF4; -.
DR   EnsemblFungi; EDN61379; EDN61379; SCY_2670.
DR   HOGENOM; CLU_792700_0_0_1; -.
DR   Proteomes; UP000007060; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Activator; Cell cycle; Cell division; Mitosis; Nucleus; Phosphoprotein;
KW   Stress response; Transcription; Transcription regulation.
FT   CHAIN           1..351
FT                   /note="Transcriptional activator POG1"
FT                   /id="PRO_0000333400"
FT   REGION          1..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          237..256
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          280..351
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..23
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        26..56
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        240..256
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        309..340
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         152
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P40473"
FT   MOD_RES         168
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P40473"
FT   MOD_RES         314
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P40473"
SQ   SEQUENCE   351 AA;  39523 MW;  14D37334944AFBF2 CRC64;
     MKQEPHRQSE EKEKPKGPMA VEREHHTSLS SGTTMTASTG DESTNSRPVE SSQTEKSLSL
     RIRILKQLGF DDIQELNACD TGLVEQFLNV RLINDTKELE KIRESNLAKL NQIIDKCMES
     DKISDSTLNK ILDMSMNRDT NNDNNNHLTI PSPITTKKRK INASELASPR GHRRYRSDIP
     TVSEVETGVG YPQIHQQPGA YTLPMPANQW MSNPYMQPPQ PQVQQIMPQY LYPPGMGPQA
     QLPTMSSNSE SQTPVMSSQF LSLNQHGLYQ QNIGAHPVMS MGPQANIYGQ QHQPQPGQER
     DQSRKSFSHR RSQSANISMA NFRSPMRNPQ PASSQRPVNF LIHTPKHPPP T