ID   POL2_ARMVS              Reviewed;        1131 AA.
AC   Q65030;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=RNA2 polyprotein;
DE   AltName: Full=P2;
DE   Contains:
DE     RecName: Full=Protein 2A;
DE              Short=P2A;
DE   Contains:
DE     RecName: Full=Movement protein;
DE     AltName: Full=2B-MP;
DE   Contains:
DE     RecName: Full=Coat protein;
DE     AltName: Full=2C-CP;
OS   Arabis mosaic virus (isolate Syrah) (ArMV).
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Picornavirales; Secoviridae; Comovirinae; Nepovirus.
OX   NCBI_TaxID=283676;
OH   NCBI_TaxID=29760; Vitis vinifera (Grape).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=9049336; DOI=10.1099/0022-1317-76-4-899;
RA   Loudes A.-M., Ritzenthaler C., Pinck M., Serghini M.A., Pinck L.;
RT   "The 119 kDa and 124 kDa polyproteins of arabis mosaic nepovirus (isolate
RT   S) are encoded by two distinct RNA2 species.";
RL   J. Gen. Virol. 76:899-906(1995).
CC   -!- FUNCTION: [Protein 2A]: Implicated in RNA2 replication. Could also be
CC       required for nematode transmission of the virus (By similarity).
CC       {ECO:0000250}.
CC   -!- FUNCTION: [Movement protein]: Transports viral genome to neighboring
CC       plant cells directly through plasmosdesmata, without any budding. The
CC       movement protein allows efficient cell to cell propagation, by
CC       bypassing the host cell wall barrier. Acts by forming a tubular
CC       structure at the host plasmodesmata, enlarging it enough to allow free
CC       passage of virion capsids (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: [Movement protein]: Host cell junction, host
CC       plasmodesma {ECO:0000250}. Note=Assembles in tubules that are embedded
CC       within modified plasmodesmata. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: [Coat protein]: Virion {ECO:0000305}.
CC   -!- PTM: Specific enzymatic cleavages in vivo by the P1 encoded 3C-like
CC       protease yield mature proteins. {ECO:0000250}.
CC   -!- MISCELLANEOUS: Virions are comprised of 60 copies of the coat protein.
CC   -!- SIMILARITY: Belongs to the nepoviruses RNA2 polyprotein family.
CC       {ECO:0000305}.
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DR   EMBL; X81814; CAA57412.1; -; Genomic_RNA.
DR   SMR; Q65030; -.
DR   GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.20; -; 2.
DR   InterPro; IPR005054; Nepo_coat.
DR   InterPro; IPR005305; Nepo_coat_C.
DR   InterPro; IPR005306; Nepo_coat_N.
DR   InterPro; IPR021081; Nepovirus_subgr_A_2A.
DR   InterPro; IPR029053; Viral_coat.
DR   Pfam; PF12312; NeA_P2; 1.
DR   Pfam; PF03391; Nepo_coat; 1.
DR   Pfam; PF03688; Nepo_coat_C; 1.
DR   Pfam; PF03689; Nepo_coat_N; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Host cell junction; Transport; Viral movement protein;
KW   Virion.
FT   CHAIN           1..277
FT                   /note="Protein 2A"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000037097"
FT   CHAIN           278..626
FT                   /note="Movement protein"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000037098"
FT   CHAIN           627..1131
FT                   /note="Coat protein"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000037099"
FT   REGION          213..236
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        220..236
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1131 AA;  124305 MW;  493F4E2B21B5EFB2 CRC64;
     MGKFYYSNRR LACYAQATNR HLGGSFEQWL QCMEDSAFRA EVKARVQSER EEVRVRRLFS
     YPVGSGPAED PRGVNWAYIC LGTTAHWAGV PGDMVPPPEP VKAQEVVVQR SVGEDGRTGY
     RRQCLNIPNP PPMPKPYSRP IGAFAPTRSG FIRATVKRLT REREESRAAA LFAELPLEYP
     QGAPLVVPRG FAAMRWTYHA TWSRWYDTSD ERALRTHPGG PALPPLPPPP PIQKPPSFEE
     RLQAALHRQS CARAFALETS LGLNMAWVGM ATIPSTSVCC ADGRTTGGQT IAQEADPLTH
     RVSSNTAPGR AQWISERRSA LRRREQANSL QGLAAQTDMT FEQARNAYLG AADMIEQGLP
     LLPPLRNAYA PRGLWRGPST RANYTLDFRL NGIPTGENTL EILYNPVSDE EMEDYRDRGM
     SAVVIDALEI AINPFGMPGN PTDLTVVATY GHERNMERAF IGSSSTFLGN GLARAIFFPG
     LQYSQEEPRR ESLIRLYVAS TNATVDADSV LAAISVGTLR QHIGSLHSRT VASSVHAAQV
     QGTTLRATMM GNSVVVSPEG GLVSGVPEAN VQIGGGSSMR MVGPLAWENV EEPGQTFSIR
     SRSRSVRVDR NADVGIAHPR MSTTTRGLAG RGTVPVPKDC QAGKYLKTLD LRDMVSGFSG
     IQYEKWITAG LVMPDFKVVI RYPANAFTGI TWVMSFDAYN RITSSISTTA SPAYTLSVPH
     WLLHHKNGTT SCDIDYGELC GHAMWFSATT FESPKLHFTC LTGNNKELAA DWEFVVELYA
     EFEAAKSFLG KPNFIYSADA FNGSLKFLTI PPLEYDLSAT SAYKSVSLLL GQTLVDGTHK
     VYNFNNTLLS YYLGIGGIVK GKVHVCSPCT YGIVLRVVSE WNGVTNNWNQ LFKYPGCYIE
     EDGSFAIEIR SPYHRTPLRL IDAQSASSFT STLNFYAISG PIAPSGETAK MPVVVQIEEI
     ALPDLSVPSF PNDYFLWVDF SSFTVDVEEY VIGSRFFDIS STTSTVALGD NPFSHMIACH
     GLHHGILDLK LMWDLEGEFG KSSGGVTITK LCGDKATGMD GASRVCALQN MGCETELYIG
     NYAGANPNTA LSLYSRWLAI KLDKAKSMKM LRILCKPRGN FEFYGRTCFK V