ID   AT326_ASPTN             Reviewed;         424 AA.
AC   Q0D158;
DT   15-FEB-2017, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Isoflavipucine cluster transcription factor ATEG_00326 {ECO:0000303|PubMed:21236704};
GN   ORFNames=ATEG_00326;
OS   Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=341663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIH 2624 / FGSC A1156;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA   Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA   Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA   Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA   Nierman W.C., Milne T., Madden K.;
RT   "Annotation of the Aspergillus terreus NIH2624 genome.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   IDENTIFICATION IN THE ISOFLAVIPUCINE CLUSTER, AND FUNCTION.
RX   PubMed=21236704; DOI=10.1016/j.chembiol.2010.12.011;
RA   Gressler M., Zaehle C., Scherlach K., Hertweck C., Brock M.;
RT   "Multifactorial induction of an orphan PKS-NRPS gene cluster in Aspergillus
RT   terreus.";
RL   Chem. Biol. 18:198-209(2011).
CC   -!- FUNCTION: Transcription factor that regulates the expression of the
CC       gene cluster that mediates the biosynthesis of isoflavipucine
CC       (PubMed:21236704). {ECO:0000305|PubMed:21236704}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
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DR   EMBL; CH476594; EAU38972.1; -; Genomic_DNA.
DR   RefSeq; XP_001210412.1; XM_001210412.1.
DR   AlphaFoldDB; Q0D158; -.
DR   SMR; Q0D158; -.
DR   EnsemblFungi; EAU38972; EAU38972; ATEG_00326.
DR   GeneID; 4355078; -.
DR   VEuPathDB; FungiDB:ATEG_00326; -.
DR   eggNOG; ENOG502STRK; Eukaryota.
DR   HOGENOM; CLU_756445_0_0_1; -.
DR   OMA; SDPGNAM; -.
DR   OrthoDB; 1030413at2759; -.
DR   Proteomes; UP000007963; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..424
FT                   /note="Isoflavipucine cluster transcription factor
FT                   ATEG_00326"
FT                   /id="PRO_0000438998"
FT   DNA_BIND        10..38
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          265..286
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        270..286
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   424 AA;  46644 MW;  C9A5E1DB54695ECF CRC64;
     MAKPNQRHAC DRCHGQKLRC IHSGGGPCVR CAKAKATCSW SQSLRSNRLK RHNVPISDVP
     LACAQLATQS TDPNTPQFGA YMSQPSSAGV DIDINLLQTQ FTDSTPWALP AGRYPSPASQ
     EMETYNVGHT EADLPTTADW MWPAVANGPV QTTPPANWQQ AFNQEWAMMA SQHPVATMNT
     PSRTSPVSDA VDPPNTVCLL ATIRELSELN VDLYAHEATV PRPPASLDEP ISWKNKDFAI
     DRTFHLSQRL IEIVNKRYPR YLETARMQTP EGTPERTSES SPSGPPLDQG SCLLVLSCYT
     RLIETYDRIF ANMQGCLDRS SVTAREDYVN MPSVQVGSFS LPHSSSLQIV LILQLARQLL
     TRMGEIIKAV QPEKGTNSAD VTLSESATGG LLLSSALETV SAEEDRLMKR ITKLRSTLIE
     LNIL