ID   POLLU_ARATH             Reviewed;         824 AA.
AC   Q9LTX4;
DT   29-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 116.
DE   RecName: Full=Probable ion channel POLLUX;
DE            Short=AtPOLLUX;
DE   AltName: Full=Probable ion channel DMI1;
GN   OrderedLocusNames=At5g49960; ORFNames=K9P8.10;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT   features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:31-63(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- SUBCELLULAR LOCATION: Nucleus membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- MISCELLANEOUS: The absence of an ortholog of CASTOR may explain the
CC       inability of Arabidopsis to form root symbioses with mycorrhizal fungi.
CC   -!- SIMILARITY: Belongs to the castor/pollux (TC 1.A.1.23) family.
CC       {ECO:0000305}.
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DR   EMBL; AB024032; BAA97017.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED95877.1; -; Genomic_DNA.
DR   RefSeq; NP_199807.1; NM_124375.3.
DR   AlphaFoldDB; Q9LTX4; -.
DR   SMR; Q9LTX4; -.
DR   STRING; 3702.AT5G49960.1; -.
DR   iPTMnet; Q9LTX4; -.
DR   SwissPalm; Q9LTX4; -.
DR   PaxDb; Q9LTX4; -.
DR   PRIDE; Q9LTX4; -.
DR   ProteomicsDB; 226288; -.
DR   EnsemblPlants; AT5G49960.1; AT5G49960.1; AT5G49960.
DR   GeneID; 835060; -.
DR   Gramene; AT5G49960.1; AT5G49960.1; AT5G49960.
DR   KEGG; ath:AT5G49960; -.
DR   Araport; AT5G49960; -.
DR   TAIR; locus:2158799; AT5G49960.
DR   eggNOG; ENOG502QU6W; Eukaryota.
DR   HOGENOM; CLU_012980_0_0_1; -.
DR   InParanoid; Q9LTX4; -.
DR   OMA; NHADTEG; -.
DR   OrthoDB; 181406at2759; -.
DR   PhylomeDB; Q9LTX4; -.
DR   PRO; PR:Q9LTX4; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9LTX4; baseline and differential.
DR   Genevisible; Q9LTX4; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR044849; CASTOR/POLLUX/SYM8-like.
DR   InterPro; IPR010420; CASTOR/POLLUX/SYM8_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR31563; PTHR31563; 1.
DR   Pfam; PF06241; Castor_Poll_mid; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Ion channel; Ion transport; Membrane; Nucleus;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..824
FT                   /note="Probable ion channel POLLUX"
FT                   /id="PRO_0000165856"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        198..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        250..270
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          45..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          325..346
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   824 AA;  92237 MW;  AC992925E4E14BD8 CRC64;
     MPIHTPRRTS LFQRSKTLPT NSYRRFTSPV IPTFRYDDGD TVSYDGDDSS NLPTVPNPEE
     KPVPVPSQSP SQRITRLWTQ FSLTHCLKFI CSCSFTYVMF LRSKVSRLEA ENIILLTRCN
     SSSDNNEMEE TNSRAVVFFS VIITFVLPFL LYMYLDDLSH VKNLLRRTNQ KKEDVPLKKR
     LAYSLDVCFS VYPYAKLLAL LLATVVLIVY GGLALYAVSD CGVDEALWLS WTFVADSGSH
     ADRVGVGARI VSVAISAGGM LIFATMLGLI SDAISKMVDS LRKGKSEVLE SNHILILGWS
     DKLGSLLKQL AIANKSIGGG VVVVLAERDK EEMETDIAKF EFDLMGTSVI CRSGSPLILA
     DLKKVSVSNA RAIIVLGSDE NADQSDARAL RVVLSLTGVK EGWKGHVVVE MCDLDNEPLV
     KLVGGERIET VVAHDVIGRL MIQCALQPGL AQIWEDILGF ENAEFYIKKW PQLDGYCFED
     VLISFPNAIP CGVKVAADGK IVLNPSDDYV LKEGDEILVI AEDDDTYAPG SLPEVRMCHF
     PKMQDPPKYP EKILFCGWRR DIDDMIKVLE ALLAPGSELW MFNEVPDQER EKKLTDAGLN
     ISKLVNIKLV HRQGNAVIRR HLESLPLETF DSILILAEQS LENSIVHSDS RSLATLLLIR
     DIQSKRLPYK DAKSSALRIS GFPNCCWIRK MQQASDKSIV ISEILDSRTK NLVSVSRISD
     YVLSNELVSM ALAMVAEDKQ INRVLKELFA EKGNELCIRP AEFYIYDQEE VCFYDIMRRA
     RQRQEIIIGY RLAGMEQAVI NPTDKSKLTK WSLDDVFVVI ASSQ