ID   AT74H_ARATH             Reviewed;         281 AA.
AC   O04035;
DT   29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 2.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=Phosphoglycerate mutase-like protein AT74H {ECO:0000305};
DE   AltName: Full=Protein At-74 homolog;
DE            Short=At-74H;
GN   OrderedLocusNames=At1g08940 {ECO:0000312|Araport:AT1G08940};
GN   ORFNames=F7G19.18 {ECO:0000312|EMBL:AAB70412.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- FUNCTION: May play a role in carbohydrates metabolism.
CC       {ECO:0000250|UniProtKB:Q9MAA2}.
CC   -!- SIMILARITY: Belongs to the phosphoglycerate mutase family.
CC       {ECO:0000305}.
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DR   EMBL; AC000106; AAB70412.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE28372.1; -; Genomic_DNA.
DR   PIR; C86221; C86221.
DR   RefSeq; NP_172369.1; NM_100766.3.
DR   AlphaFoldDB; O04035; -.
DR   SMR; O04035; -.
DR   PaxDb; O04035; -.
DR   PRIDE; O04035; -.
DR   ProteomicsDB; 246824; -.
DR   EnsemblPlants; AT1G08940.1; AT1G08940.1; AT1G08940.
DR   GeneID; 837415; -.
DR   Gramene; AT1G08940.1; AT1G08940.1; AT1G08940.
DR   KEGG; ath:AT1G08940; -.
DR   Araport; AT1G08940; -.
DR   TAIR; locus:2036069; AT1G08940.
DR   eggNOG; ENOG502QTHF; Eukaryota.
DR   HOGENOM; CLU_033323_3_2_1; -.
DR   InParanoid; O04035; -.
DR   OMA; NDSCSLH; -.
DR   OrthoDB; 800109at2759; -.
DR   PhylomeDB; O04035; -.
DR   PRO; PR:O04035; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; O04035; baseline and differential.
DR   Genevisible; O04035; AT.
DR   GO; GO:0016791; F:phosphatase activity; IBA:GO_Central.
DR   CDD; cd07067; HP_PGM_like; 1.
DR   Gene3D; 3.40.50.1240; -; 1.
DR   InterPro; IPR013078; His_Pase_superF_clade-1.
DR   InterPro; IPR029033; His_PPase_superfam.
DR   InterPro; IPR001345; PG/BPGM_mutase_AS.
DR   Pfam; PF00300; His_Phos_1; 1.
DR   SMART; SM00855; PGAM; 1.
DR   SUPFAM; SSF53254; SSF53254; 1.
DR   PROSITE; PS00175; PG_MUTASE; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..281
FT                   /note="Phosphoglycerate mutase-like protein AT74H"
FT                   /id="PRO_0000430636"
FT   ACT_SITE        17
FT                   /note="Tele-phosphohistidine intermediate"
FT                   /evidence="ECO:0000250|UniProtKB:P62707"
FT   ACT_SITE        109
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000250|UniProtKB:P62707"
SQ   SEQUENCE   281 AA;  32679 MW;  220F10A296C6290D CRC64;
     MVNEKKMLPK RIILMRHGES AGNIDAGAYA TTPDHKIPLT EEGRAQAREA GKKMRALIST
     QSGGACGENW RVYFYVSPYE RTRTTLREVG KGFSRKRVIG VREECRIREQ DFGNFQVEER
     MRVVKETRER FGRFFYRFPE GESAADVYDR VSSFLESMWR DVDMNRHQVD PSSELNLVIV
     SHGLTSRVFL TKWFKWTVAE FERLNNFGNC EFRVMELGAS GEYTFAIHHS EEEMLDWGMS
     KDMIDDQKDR VDGCRVTTSN DSCSLHLNEY FDLLDVTDDE E