AT74_ARATH
ID AT74_ARATH Reviewed; 316 AA.
AC Q9MAA2; Q0WMW9;
DT 29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Phosphoglycerate mutase-like protein AT74 {ECO:0000305};
DE Short=At-74 {ECO:0000303|PubMed:15737980};
GN OrderedLocusNames=At3g05170 {ECO:0000312|Araport:AT3G05170};
GN ORFNames=T12H1.14 {ECO:0000312|EMBL:AAF27023.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-284.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP FUNCTION, TISSUE SPECIFICITY, AND INDUCTION BY SUCROSE.
RX PubMed=15737980; DOI=10.1093/jxb/eri105;
RA Bourgis F., Botha F.C., Mani S., Hiten F.N., Rigden D.J., Verbruggen N.;
RT "Characterization and functional investigation of an Arabidopsis cDNA
RT encoding a homologue to the d-PGMase superfamily.";
RL J. Exp. Bot. 56:1129-1142(2005).
CC -!- FUNCTION: Phosphoglycerate mutase-like protein lacking PGM activity.
CC May play a role in carbohydrates metabolism.
CC {ECO:0000269|PubMed:15737980}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, leaves, stems, flowers and
CC siliques. {ECO:0000269|PubMed:15737980}.
CC -!- INDUCTION: By sucrose. {ECO:0000269|PubMed:15737980}.
CC -!- SIMILARITY: Belongs to the phosphoglycerate mutase family.
CC {ECO:0000305}.
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DR EMBL; AC009177; AAF27023.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE74200.1; -; Genomic_DNA.
DR EMBL; AK229691; BAF01531.1; -; mRNA.
DR RefSeq; NP_187168.1; NM_111390.2.
DR AlphaFoldDB; Q9MAA2; -.
DR SMR; Q9MAA2; -.
DR STRING; 3702.AT3G05170.1; -.
DR PaxDb; Q9MAA2; -.
DR PRIDE; Q9MAA2; -.
DR ProteomicsDB; 246825; -.
DR EnsemblPlants; AT3G05170.1; AT3G05170.1; AT3G05170.
DR GeneID; 819681; -.
DR Gramene; AT3G05170.1; AT3G05170.1; AT3G05170.
DR KEGG; ath:AT3G05170; -.
DR Araport; AT3G05170; -.
DR TAIR; locus:2096249; AT3G05170.
DR eggNOG; ENOG502QTHF; Eukaryota.
DR HOGENOM; CLU_033323_3_2_1; -.
DR InParanoid; Q9MAA2; -.
DR OMA; HMADSDQ; -.
DR OrthoDB; 800109at2759; -.
DR PhylomeDB; Q9MAA2; -.
DR PRO; PR:Q9MAA2; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9MAA2; baseline and differential.
DR Genevisible; Q9MAA2; AT.
DR GO; GO:0016791; F:phosphatase activity; IBA:GO_Central.
DR GO; GO:0005975; P:carbohydrate metabolic process; TAS:UniProtKB.
DR CDD; cd07067; HP_PGM_like; 1.
DR Gene3D; 3.40.50.1240; -; 1.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR001345; PG/BPGM_mutase_AS.
DR Pfam; PF00300; His_Phos_1; 1.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF53254; SSF53254; 1.
DR PROSITE; PS00175; PG_MUTASE; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..316
FT /note="Phosphoglycerate mutase-like protein AT74"
FT /id="PRO_0000430635"
FT REGION 275..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..316
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 17
FT /note="Tele-phosphohistidine intermediate"
FT /evidence="ECO:0000250|UniProtKB:P62707"
FT ACT_SITE 106
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000250|UniProtKB:P62707"
SQ SEQUENCE 316 AA; 36880 MW; 84929674BE351F08 CRC64;
MSPDNKLLPK RIILVRHGES EGNLDTAAYT TTPDHKIQLT DSGLLQAQEA GARLHALISS
NPSSPEWRVY FYVSPYDRTR STLREIGRSF SRRRVIGVRE ECRIREQDFG NFQVKERMRA
TKKVRERFGR FFYRFPEGES AADVFDRVSS FLESLWRDID MNRLHINPSH ELNFVIVSHG
LTSRVFLMKW FKWSVEQFEG LNNPGNSEIR VMELGQGGDY SLAIHHTEEE LATWGLSPEM
IADQKWRANA HKGEWKEDCK WYFGDFFDHM ADSDKECETE ATEDREEEEE EEGKRVNLLT
SSEYSNEPEL YNGQCC
