POMP_DICDI
ID POMP_DICDI Reviewed; 128 AA.
AC Q55G18;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=Proteasome maturation protein homolog;
GN Name=pomp; ORFNames=DDB_G0267866;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- FUNCTION: May function as molecular chaperone essential for the
CC assembly of standard proteasomes and immunoproteasomes. Degraded after
CC completion of proteasome maturation (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Constituent of preproteasomes, but not of mature 20S
CC proteasomes. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250}. Nucleus
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the POMP/UMP1 family. {ECO:0000305}.
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DR EMBL; AAFI02000003; EAL73386.1; -; Genomic_DNA.
DR RefSeq; XP_647365.1; XM_642273.1.
DR AlphaFoldDB; Q55G18; -.
DR STRING; 44689.DDB0237641; -.
DR PaxDb; Q55G18; -.
DR EnsemblProtists; EAL73386; EAL73386; DDB_G0267866.
DR GeneID; 8616176; -.
DR KEGG; ddi:DDB_G0267866; -.
DR dictyBase; DDB_G0267866; -.
DR eggNOG; KOG3061; Eukaryota.
DR HOGENOM; CLU_1963699_0_0_1; -.
DR InParanoid; Q55G18; -.
DR OMA; WDEKKRF; -.
DR PhylomeDB; Q55G18; -.
DR PRO; PR:Q55G18; -.
DR Proteomes; UP000002195; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0043248; P:proteasome assembly; IBA:GO_Central.
DR InterPro; IPR008012; Ump1.
DR PANTHER; PTHR12828; PTHR12828; 1.
DR Pfam; PF05348; UMP1; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Nucleus; Reference proteome.
FT CHAIN 1..128
FT /note="Proteasome maturation protein homolog"
FT /id="PRO_0000328311"
SQ SEQUENCE 128 AA; 14399 MW; A74E528C8E9F6478 CRC64;
MQSIVKKDLD LPTLRNESSN VKGLSHPVES IQLDQGKTEI KLKNFAMKNV FGTHMVMNNE
IEKQIYSQFK RLPTLQSSMV GLETILGLDE DFDFGDYLCD PATSEAPLPQ LHTSMEHRLG
MTSSKSIL