PON1B_ANOEM
ID PON1B_ANOEM Reviewed; 18 AA.
AC C0HJY5;
DT 02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 02-NOV-2016, sequence version 1.
DT 25-MAY-2022, entry version 11.
DE RecName: Full=U1-poneritoxin-Ae1b {ECO:0000303|PubMed:27474999};
DE Short=U1-PONTX-Ae1b {ECO:0000303|PubMed:27474999};
DE AltName: Full=Poneratoxin {ECO:0000305};
OS Anochetus emarginatus (Ant) (Stenomyrmex emarginatus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Anochetus.
OX NCBI_TaxID=486636;
RN [1]
RP PROTEIN SEQUENCE, SUBCELLULAR LOCATION, MASS SPECTROMETRY, AMIDATION AT
RP CYS-18, AND IDENTIFICATION BY MASS SPECTROMETRY.
RC TISSUE=Venom;
RX PubMed=27474999; DOI=10.1016/j.bbagen.2016.07.027;
RA Touchard A., Brust A., Cardoso F., Chin Y.-K., Herzig V., Jin A.-H.,
RA Dejean A., Alewood P., King G., Orivel J., Escoubas P.;
RT "Isolation and characterization of a structurally unique beta-hairpin venom
RT peptide from the predatory ant Anochetus emarginatus.";
RL Biochim. Biophys. Acta 1860:2553-2562(2016).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:27474999}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC {ECO:0000305|PubMed:27474999}.
CC -!- MASS SPECTROMETRY: Mass=1916.96; Mass_error=0.2; Method=MALDI;
CC Evidence={ECO:0000269|PubMed:27474999};
CC -!- SIMILARITY: Belongs to the poneritoxin-Ae1 family. {ECO:0000305}.
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DR AlphaFoldDB; C0HJY5; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Disulfide bond; Secreted; Toxin.
FT PEPTIDE 1..18
FT /note="U1-poneritoxin-Ae1b"
FT /evidence="ECO:0000269|PubMed:27474999"
FT /id="PRO_0000437874"
FT MOD_RES 18
FT /note="Cysteine amide"
FT /evidence="ECO:0000269|PubMed:27474999"
FT DISULFID 3..16
FT /evidence="ECO:0000250|UniProtKB:C0HJY4"
FT DISULFID 7..18
FT /evidence="ECO:0000250|UniProtKB:C0HJY4"
SQ SEQUENCE 18 AA; 1922 MW; 83C97390A0A5F105 CRC64;
RYCPSGCRKK PYGGGCSC