ID   POP7_BOVIN              Reviewed;         140 AA.
AC   Q0II25;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Ribonuclease P protein subunit p20;
DE            Short=RNaseP protein p20;
GN   Name=POP7; Synonyms=RPP20;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Hypothalamus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of ribonuclease P, a ribonucleoprotein complex that
CC       generates mature tRNA molecules by cleaving their 5'-ends. Also a
CC       component of the MRP ribonuclease complex, which cleaves pre-rRNA
CC       sequences. {ECO:0000250|UniProtKB:O75817}.
CC   -!- SUBUNIT: Component of nuclear RNase P and RNase MRP complexes. RNase P
CC       consists of a catalytic RNA moiety and 10 different protein chains;
CC       POP1, POP4, POP5, POP7, RPP14, RPP21, RPP25, RPP30, RPP38 and RPP40.
CC       Within the RNase P complex, POP1, POP7 and RPP25 form the 'finger'
CC       subcomplex, POP5, RPP14, RPP40 and homodimeric RPP30 form the 'palm'
CC       subcomplex, and RPP21, POP4 and RPP38 form the 'wrist' subcomplex. All
CC       subunits of the RNase P complex interact with the catalytic RNA.
CC       Several subunits of RNase P are also part of the RNase MRP complex.
CC       RNase MRP consists of a catalytic RNA moiety and about 8 protein
CC       subunits; POP1, POP7, RPP25, RPP30, RPP38, RPP40 and possibly also POP4
CC       and POP5. Interacts with SMN1. POP7 forms a heterodimer with RPP25 that
CC       binds to the P3 stem loop of the catalytic RNA.
CC       {ECO:0000250|UniProtKB:O75817}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:O75817}. Cytoplasm
CC       {ECO:0000250|UniProtKB:O75817}. Cytoplasmic granule
CC       {ECO:0000250|UniProtKB:O75817}. Note=Under stress conditions
CC       colocalizes with SMN1 in punctuated cytoplasmic granules.
CC       {ECO:0000250|UniProtKB:O75817}.
CC   -!- SIMILARITY: Belongs to the histone-like Alba family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC122839; AAI22840.1; -; mRNA.
DR   RefSeq; NP_001069950.1; NM_001076482.2.
DR   RefSeq; XP_005225275.1; XM_005225218.1.
DR   RefSeq; XP_005225276.1; XM_005225219.1.
DR   RefSeq; XP_015315985.1; XM_015460499.1.
DR   AlphaFoldDB; Q0II25; -.
DR   SMR; Q0II25; -.
DR   STRING; 9913.ENSBTAP00000037068; -.
DR   PaxDb; Q0II25; -.
DR   PRIDE; Q0II25; -.
DR   GeneID; 617906; -.
DR   KEGG; bta:617906; -.
DR   CTD; 10248; -.
DR   eggNOG; KOG3631; Eukaryota.
DR   HOGENOM; CLU_130587_1_0_1; -.
DR   InParanoid; Q0II25; -.
DR   OrthoDB; 1433955at2759; -.
DR   TreeFam; TF313948; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030681; C:multimeric ribonuclease P complex; ISS:UniProtKB.
DR   GO; GO:0005655; C:nucleolar ribonuclease P complex; IEA:InterPro.
DR   GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0000172; C:ribonuclease MRP complex; IEA:InterPro.
DR   GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-EC.
DR   GO; GO:0033204; F:ribonuclease P RNA binding; ISS:UniProtKB.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; IBA:GO_Central.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0001682; P:tRNA 5'-leader removal; ISS:UniProtKB.
DR   GO; GO:0008033; P:tRNA processing; IBA:GO_Central.
DR   Gene3D; 3.30.110.20; -; 1.
DR   InterPro; IPR036882; Alba-like_dom_sf.
DR   InterPro; IPR014612; Pop7/Rpp20.
DR   PANTHER; PTHR15314; PTHR15314; 1.
DR   Pfam; PF12328; Rpp20; 1.
DR   PIRSF; PIRSF036572; RPP20; 1.
DR   SUPFAM; SSF82704; SSF82704; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Reference proteome; rRNA processing; tRNA processing.
FT   CHAIN           1..140
FT                   /note="Ribonuclease P protein subunit p20"
FT                   /id="PRO_0000271034"
SQ   SEQUENCE   140 AA;  15707 MW;  7E4E130FF44B6BB4 CRC64;
     MAENRESRGT VEAELDPVEY TLRKRLPHRL PRRPNDIYVN MKTDFKAQLA RCQKLLDGGA
     RGQNACSEIY IHGLGLAINR AINIALQLQA GSFGSLQVAA NTSTVELVDE LEPETDSREP
     LTRIRNNSAI HIRVFRVTPK