ID   POP8_SCHPO              Reviewed;         108 AA.
AC   Q7Z996;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Probable ribonucleases P protein subunit pop8;
DE            EC=3.1.26.5;
GN   Name=pop8; ORFNames=SPBC1709.20;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Part of ribonuclease P, a protein complex that generates
CC       mature tRNA molecules by cleaving their 5'-ends. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endonucleolytic cleavage of RNA, removing 5'-extranucleotides
CC         from tRNA precursor.; EC=3.1.26.5;
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR   EMBL; CU329671; CAD99064.1; -; Genomic_DNA.
DR   RefSeq; NP_001018786.1; NM_001021349.1.
DR   AlphaFoldDB; Q7Z996; -.
DR   SMR; Q7Z996; -.
DR   BioGRID; 280349; 3.
DR   STRING; 4896.SPBC1709.20.1; -.
DR   PaxDb; Q7Z996; -.
DR   PRIDE; Q7Z996; -.
DR   EnsemblFungi; SPBC1709.20.1; SPBC1709.20.1:pep; SPBC1709.20.
DR   GeneID; 3361273; -.
DR   KEGG; spo:SPBC1709.20; -.
DR   PomBase; SPBC1709.20; pop8.
DR   VEuPathDB; FungiDB:SPBC1709.20; -.
DR   HOGENOM; CLU_2198514_0_0_1; -.
DR   InParanoid; Q7Z996; -.
DR   OMA; LRCHIND; -.
DR   PhylomeDB; Q7Z996; -.
DR   PRO; PR:Q7Z996; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005655; C:nucleolar ribonuclease P complex; ISO:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0000172; C:ribonuclease MRP complex; EXP:PomBase.
DR   GO; GO:0004526; F:ribonuclease P activity; ISO:PomBase.
DR   GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IDA:PomBase.
DR   GO; GO:1905267; P:endonucleolytic cleavage involved in tRNA processing; IDA:PomBase.
DR   GO; GO:0034965; P:intronic box C/D RNA processing; IBA:GO_Central.
DR   GO; GO:0006379; P:mRNA cleavage; IEA:InterPro.
DR   GO; GO:0000294; P:nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay; IBA:GO_Central.
DR   GO; GO:0008033; P:tRNA processing; IBA:GO_Central.
DR   InterPro; IPR020347; Pop8.
DR   InterPro; IPR038085; Rnp2-like_sf.
DR   PANTHER; PTHR28173; PTHR28173; 1.
DR   SUPFAM; SSF160350; SSF160350; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Nucleus; Reference proteome; tRNA processing.
FT   CHAIN           1..108
FT                   /note="Probable ribonucleases P protein subunit pop8"
FT                   /id="PRO_0000058520"
SQ   SEQUENCE   108 AA;  12379 MW;  9194B49D86C4718A CRC64;
     MVLHQRLKSE WSYIILEVVG GTTPIDEIDD ISLRHLITLA LNQSFGIFGS AIPIDFLHRQ
     SKFLYLRCHK EDKKKVLVAL GSYVREPEQI RLMVLHASDF PCQAVPFS