ID   PORA_CORRG              Reviewed;         413 AA.
AC   F8DYT7;
DT   01-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT   21-SEP-2011, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=Porin PorA {ECO:0000303|PubMed:23811360};
DE   Flags: Precursor;
GN   Name=porA {ECO:0000303|PubMed:23811360}; OrderedLocusNames=CRES_0567;
OS   Corynebacterium resistens (strain DSM 45100 / JCM 12819 / GTC 2026 / SICGH
OS   158).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=662755;
RN   [1] {ECO:0000312|EMBL:AEI08929.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45100 / JCM 12819 / GTC 2026 / SICGH 158;
RX   PubMed=22524407; DOI=10.1186/1471-2164-13-141;
RA   Schroder J., Maus I., Meyer K., Wordemann S., Blom J., Jaenicke S.,
RA   Schneider J., Trost E., Tauch A.;
RT   "Complete genome sequence, lifestyle, and multi-drug resistance of the
RT   human pathogen Corynebacterium resistens DSM 45100 isolated from blood
RT   samples of a leukemia patient.";
RL   BMC Genomics 13:141-141(2012).
RN   [2] {ECO:0000305}
RP   FUNCTION.
RC   STRAIN=DSM 45100 / JCM 12819 / GTC 2026 / SICGH 158
RC   {ECO:0000269|PubMed:23811360};
RX   PubMed=23811360; DOI=10.1016/j.bbamem.2013.06.024;
RA   Soltan Mohammadi N., Mafakheri S., Abdali N., Barcena-Uribarri I.,
RA   Tauch A., Benz R.;
RT   "Identification and characterization of the channel-forming protein in the
RT   cell wall of Corynebacterium amycolatum.";
RL   Biochim. Biophys. Acta 1828:2574-2582(2013).
CC   -!- FUNCTION: Forms water-filled channels that favor the permeation of
CC       cations. {ECO:0000269|PubMed:23811360}.
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall
CC       {ECO:0000250|UniProtKB:C0HJE6}. Note=Probably part of the
CC       corynemycolate layer which forms a structure similar to the outer
CC       membrane found in Gram-negative bacteria.
CC       {ECO:0000250|UniProtKB:C0HJE6, ECO:0000305|PubMed:22524407}.
CC   -!- SIMILARITY: Belongs to the PorA family. {ECO:0000305}.
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DR   EMBL; CP002857; AEI08929.1; -; Genomic_DNA.
DR   RefSeq; WP_013887954.1; NC_015673.1.
DR   AlphaFoldDB; F8DYT7; -.
DR   SMR; F8DYT7; -.
DR   STRING; 662755.CRES_0567; -.
DR   EnsemblBacteria; AEI08929; AEI08929; CRES_0567.
DR   KEGG; crd:CRES_0567; -.
DR   eggNOG; ENOG5031U1J; Bacteria.
DR   HOGENOM; CLU_045231_1_0_11; -.
DR   OMA; PIAQKPF; -.
DR   OrthoDB; 1593423at2; -.
DR   Proteomes; UP000000492; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR021424; PorA.
DR   Pfam; PF11271; PorA; 1.
PE   3: Inferred from homology;
KW   Cell wall; Ion transport; Reference proteome; Secreted; Signal; Transport.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..413
FT                   /note="Porin PorA"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000430485"
FT   REGION          265..288
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        266..288
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   413 AA;  45983 MW;  574357F174AEEB0F CRC64;
     MKKVVSSLLI ILGAAMLIFA IALPTYVVPK GKVLPKDIVS TTGTDPIKGN LLDASALAEG
     KPVSGKENLP ECRGKDKQVS CFIWKDLELQ SQRFTRAQEP TDDKVVTLEA GQTLFRTDRQ
     EPKNLVNATV DRVTLDRKTQ MPVADPVSTL DVNAPALNPN GEAAIGPFTR PGIQYQFPMG
     TDRRSYDYFD TQALKAQPID YVGEEEQDGE KVYKFEQTVS PVELYPRLKE QLEADGDLSK
     ADQSTLASLR LKFPAKVWGI EGADTKSAAD SKDDKKKDGD KKDEKSPEVE LSRYYTVKRT
     LWVQPDTGVI VNGKEDIWQF YAKDQDEADK MAQPENREKE MNNPKRTALY IPGAWNDESR
     AAQMDKAKEG LKTLKTMGTT VPWILGPLGL LLLLVGLVMA LKRRRAERHA NAL