PORC_METJA
ID PORC_METJA Reviewed; 178 AA.
AC Q57717;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 106.
DE RecName: Full=Pyruvate synthase subunit PorC;
DE EC=1.2.7.1;
DE AltName: Full=Pyruvate oxidoreductase gamma chain;
DE Short=POR;
DE AltName: Full=Pyruvic-ferredoxin oxidoreductase subunit gamma;
GN Name=porC; OrderedLocusNames=MJ0269;
OS Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS 10045 / NBRC 100440) (Methanococcus jannaschii).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanocaldococcus.
OX NCBI_TaxID=243232;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT jannaschii.";
RL Science 273:1058-1073(1996).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA
CC + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]; Xref=Rhea:RHEA:12765,
CC Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001, ChEBI:CHEBI:15361,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:33737,
CC ChEBI:CHEBI:33738, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=1.2.7.1;
CC -!- SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one gamma
CC chain.
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DR EMBL; L77117; AAB98256.1; -; Genomic_DNA.
DR PIR; F64333; F64333.
DR RefSeq; WP_010869766.1; NC_000909.1.
DR AlphaFoldDB; Q57717; -.
DR SMR; Q57717; -.
DR STRING; 243232.MJ_0269; -.
DR EnsemblBacteria; AAB98256; AAB98256; MJ_0269.
DR GeneID; 1451123; -.
DR KEGG; mja:MJ_0269; -.
DR eggNOG; arCOG01603; Archaea.
DR HOGENOM; CLU_087284_2_0_2; -.
DR InParanoid; Q57717; -.
DR OMA; PDYVIVQ; -.
DR OrthoDB; 95610at2157; -.
DR PhylomeDB; Q57717; -.
DR Proteomes; UP000000805; Chromosome.
DR GO; GO:0019164; F:pyruvate synthase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.920.10; -; 1.
DR InterPro; IPR011894; PorC_KorC.
DR InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR Pfam; PF01558; POR; 1.
DR SUPFAM; SSF53323; SSF53323; 1.
DR TIGRFAMs; TIGR02175; PorC_KorC; 1.
PE 4: Predicted;
KW Oxidoreductase; Reference proteome.
FT CHAIN 1..178
FT /note="Pyruvate synthase subunit PorC"
FT /id="PRO_0000099910"
SQ SEQUENCE 178 AA; 19202 MW; 3758EE7EC70FAEE1 CRC64;
MIEIRFHGRG GQGAVTAAQI LAKAAFYDGK FCQAFPFFGV ERRGAPVMAF TRIDDKKITL
RCQIYEPDYV IVQDATLLES VNVVEGLKKD GAVVINTVKD DLDLGYKTYT IDATGIALDV
LGVPIVNTAM VGAFAGVTGI VSIESVKKAI LDTFKGKLGE KNAKAAEVAY NEMLKKYG