ID   PORC_METTH              Reviewed;         180 AA.
AC   O27772;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 2.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Pyruvate synthase subunit PorC;
DE            EC=1.2.7.1;
DE   AltName: Full=Pyruvate oxidoreductase gamma chain;
DE            Short=POR;
DE   AltName: Full=Pyruvic-ferredoxin oxidoreductase subunit gamma;
GN   Name=porC; OrderedLocusNames=MTH_1740;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA
CC         + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]; Xref=Rhea:RHEA:12765,
CC         Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001, ChEBI:CHEBI:15361,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:33737,
CC         ChEBI:CHEBI:33738, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=1.2.7.1;
CC   -!- SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one gamma
CC       chain.
CC   -!- CAUTION: There seems to be a sequencing error that fuses together porC
CC       and porD. We have cut the ORF into its two constituents. {ECO:0000305}.
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DR   EMBL; AE000666; AAB86210.1; ALT_TERM; Genomic_DNA.
DR   AlphaFoldDB; O27772; -.
DR   SMR; O27772; -.
DR   STRING; 187420.MTH_1740; -.
DR   EnsemblBacteria; AAB86210; AAB86210; MTH_1740.
DR   KEGG; mth:MTH_1740; -.
DR   HOGENOM; CLU_060916_0_0_2; -.
DR   OMA; PDYVIVQ; -.
DR   BioCyc; MetaCyc:MON-14531; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0019164; F:pyruvate synthase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.920.10; -; 1.
DR   InterPro; IPR011894; PorC_KorC.
DR   InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR   InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR   Pfam; PF01558; POR; 1.
DR   SUPFAM; SSF53323; SSF53323; 1.
DR   TIGRFAMs; TIGR02175; PorC_KorC; 1.
PE   4: Predicted;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..180
FT                   /note="Pyruvate synthase subunit PorC"
FT                   /id="PRO_0000099911"
SQ   SEQUENCE   180 AA;  19524 MW;  F209CCFF749B2032 CRC64;
     MIEIRFHGRG GQGAVTAAEI LAKAAFEDGK YSQAFPFFGV ERRGAPVMAF TRIDDSPVRR
     RYQVYNPDYV VVLDEGLVDV VDVFSGLKDD GVVVLNKSGD FQGGDVKVHT IDATGIALET
     LGRPIVNTVM LGAFAGVTGL VSIDSLIKII KETFPGKIGE KNAEAARMAY EEIEKLRVNM