ID   PORC_METTM              Reviewed;         177 AA.
AC   P80902; D9PUM4;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   30-NOV-2010, sequence version 2.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Pyruvate synthase subunit PorC;
DE            EC=1.2.7.1;
DE   AltName: Full=Pyruvate oxidoreductase gamma chain;
DE            Short=POR;
DE   AltName: Full=Pyruvic-ferredoxin oxidoreductase subunit gamma;
GN   Name=porC; OrderedLocusNames=MTBMA_c03160;
OS   Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM
OS   14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium
OS   thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=79929;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 /
RC   Marburg;
RX   PubMed=20802048; DOI=10.1128/jb.00844-10;
RA   Liesegang H., Kaster A.K., Wiezer A., Goenrich M., Wollherr A., Seedorf H.,
RA   Gottschalk G., Thauer R.K.;
RT   "Complete genome sequence of Methanothermobacter marburgensis, a
RT   methanoarchaeon model organism.";
RL   J. Bacteriol. 192:5850-5851(2010).
RN   [2]
RP   PROTEIN SEQUENCE OF 1-20, BIOPHYSICOCHEMICAL PROPERTIES, AND SUBUNIT.
RC   STRAIN=ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 /
RC   Marburg;
RX   PubMed=9108258; DOI=10.1111/j.1432-1033.1997.00862.x;
RA   Tersteegen A., Linder D., Thauer R.K., Hedderich R.;
RT   "Structures and functions of four anabolic 2-oxoacid oxidoreductases in
RT   Methanobacterium thermoautotrophicum.";
RL   Eur. J. Biochem. 244:862-868(1997).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA
CC         + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]; Xref=Rhea:RHEA:12765,
CC         Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001, ChEBI:CHEBI:15361,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:33737,
CC         ChEBI:CHEBI:33738, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=1.2.7.1;
CC   -!- BIOPHYSICOCHEMICAL PROPERTIES:
CC       pH dependence:
CC         Optimum pH is 10.0. {ECO:0000269|PubMed:9108258};
CC       Temperature dependence:
CC         Optimum temperature is 80 degrees Celsius.
CC         {ECO:0000269|PubMed:9108258};
CC   -!- SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one gamma
CC       chain. {ECO:0000269|PubMed:9108258}.
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DR   EMBL; CP001710; ADL57922.1; -; Genomic_DNA.
DR   RefSeq; WP_013295149.1; NC_014408.1.
DR   AlphaFoldDB; P80902; -.
DR   SMR; P80902; -.
DR   STRING; 79929.MTBMA_c03160; -.
DR   EnsemblBacteria; ADL57922; ADL57922; MTBMA_c03160.
DR   GeneID; 9704022; -.
DR   KEGG; mmg:MTBMA_c03160; -.
DR   HOGENOM; CLU_087284_2_0_2; -.
DR   OMA; PDYVIVQ; -.
DR   OrthoDB; 95610at2157; -.
DR   Proteomes; UP000000345; Chromosome.
DR   GO; GO:0019164; F:pyruvate synthase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.920.10; -; 1.
DR   InterPro; IPR011894; PorC_KorC.
DR   InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR   InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR   Pfam; PF01558; POR; 1.
DR   SUPFAM; SSF53323; SSF53323; 1.
DR   TIGRFAMs; TIGR02175; PorC_KorC; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Oxidoreductase.
FT   CHAIN           1..177
FT                   /note="Pyruvate synthase subunit PorC"
FT                   /id="PRO_0000099912"
SQ   SEQUENCE   177 AA;  19147 MW;  62A3E2099CB4986B CRC64;
     MIEIRFHGRG GQGAVTAAEI LAKAAFEDGK YSQAFPFFGV ERRGAPVMAF TRINDEPIRR
     RYQVYNPDYV VVLDEGLVDV VDVFSGLKED GVVLLNTAGT FTSENAKIHT IDATGIALEN
     LGRPIVNTVM LGAFAGVTGL VSIDSLIKII KETFPGKIGD KNAEAARIAY EKMKHSG