ID   PORC_PYREN              Reviewed;          15 AA.
AC   P84819; Q9UWG1;
DT   02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   02-MAY-2006, sequence version 1.
DT   11-DEC-2019, entry version 26.
DE   RecName: Full=Pyruvate/ketoisovalerate oxidoreductases common subunit gamma;
DE   Includes:
DE     RecName: Full=Pyruvate synthase subunit PorC;
DE              EC=1.2.7.1;
DE     AltName: Full=Pyruvate oxidoreductase gamma chain;
DE              Short=POR;
DE     AltName: Full=Pyruvic-ferredoxin oxidoreductase subunit gamma;
DE   Includes:
DE     RecName: Full=Ketoisovalerate oxidoreductase subunit VorC;
DE              Short=VOR;
DE              EC=1.2.7.7;
DE     AltName: Full=2-oxoisovalerate ferredoxin reductase subunit gamma;
DE     AltName: Full=2-oxoisovalerate oxidoreductase gamma chain;
DE   Flags: Fragment;
GN   Name=porG;
OS   Pyrococcus endeavori.
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=39456;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE.
RX   PubMed=8550513; DOI=10.1128/jb.178.3.780-787.1996;
RA   Heider J., Mai X., Adams M.W.W.;
RT   "Characterization of 2-ketoisovalerate ferredoxin oxidoreductase, a new and
RT   reversible coenzyme A-dependent enzyme involved in peptide fermentation by
RT   hyperthermophilic archaea.";
RL   J. Bacteriol. 178:780-787(1996).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA
CC         + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]; Xref=Rhea:RHEA:12765,
CC         Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001, ChEBI:CHEBI:15361,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:33737,
CC         ChEBI:CHEBI:33738, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=1.2.7.1;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=3-methyl-2-oxobutanoate + CoA + 2 oxidized [2Fe-2S]-
CC         [ferredoxin] = 2-methylpropanoyl-CoA + CO2 + H(+) + 2 reduced [2Fe-
CC         2S]-[ferredoxin]; Xref=Rhea:RHEA:11712, Rhea:RHEA-COMP:10000,
CC         Rhea:RHEA-COMP:10001, ChEBI:CHEBI:11851, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:33737, ChEBI:CHEBI:33738,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57338; EC=1.2.7.7;
CC   -!- SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one gamma
CC       chain. {ECO:0000250|UniProtKB:Q51799}.
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DR   GO; GO:0043807; F:3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity; IEA:UniProtKB-EC.
DR   GO; GO:0019164; F:pyruvate synthase activity; IEA:UniProtKB-EC.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Oxidoreductase.
FT   CHAIN           1..>15
FT                   /note="Pyruvate/ketoisovalerate oxidoreductases common
FT                   subunit gamma"
FT                   /id="PRO_0000233957"
FT   NON_TER         15
FT                   /evidence="ECO:0000250|UniProtKB:Q51799"
SQ   SEQUENCE   15 AA;  1628 MW;  32F341A6A0331631 CRC64;
     MIEIRFHGRG GQGAV