ID   PORFL_POTOR             Reviewed;          18 AA.
AC   P86295;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   25-MAY-2022, entry version 11.
DE   RecName: Full=Porflan;
OS   Potamotrygon orbignyi (Smooth back river stingray).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Batoidea; Myliobatiformes; Potamotrygonidae; Potamotrygon.
OX   NCBI_TaxID=86381;
RN   [1]
RP   PROTEIN SEQUENCE, FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND
RP   MASS SPECTROMETRY.
RC   TISSUE=Venom;
RX   PubMed=19682520; DOI=10.1016/j.peptides.2009.08.004;
RA   Conceicao K., Santos J.M., Bruni F.M., Klitzke C.F., Marques E.E.,
RA   Borges M.H., Melo R.L., Fernandez J.H., Lopes-Ferreira M.;
RT   "Characterization of a new bioactive peptide from Potamotrygon gr. orbignyi
RT   freshwater stingray venom.";
RL   Peptides 30:2191-2199(2009).
CC   -!- FUNCTION: Inflammatory peptide. Induces leukocyte recruitment and
CC       adherence to the vascular endothelium when applied to mouse cremaster
CC       muscle. {ECO:0000269|PubMed:19682520}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:19682520}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC       {ECO:0000269|PubMed:19682520}.
CC   -!- MASS SPECTROMETRY: Mass=2006.091; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:19682520};
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DR   AlphaFoldDB; P86295; -.
DR   GO; GO:0005576; C:extracellular region; IDA:UniProtKB.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0002687; P:positive regulation of leukocyte migration; IDA:UniProtKB.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Secreted; Toxin.
FT   PEPTIDE         1..18
FT                   /note="Porflan"
FT                   /id="PRO_0000378074"
SQ   SEQUENCE   18 AA;  2006 MW;  9ED2404E4E551BE9 CRC64;
     ESIVRPPPVE AKVEETPE