ID   PORI_BPPA2              Reviewed;         365 AA.
AC   P07238;
DT   01-APR-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1988, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Outer membrane porin protein LC;
DE   Flags: Precursor;
GN   Name=LC;
OS   Enterobacteria phage PA-2 (Bacteriophage PA-2).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae; Lambdavirus; unclassified Lambdavirus.
OX   NCBI_TaxID=10738;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3017988; DOI=10.1016/s0021-9258(18)67152-2;
RA   Blasband A.J., Marcotte W.R. Jr., Schnaitman C.A.;
RT   "Structure of the lc and nmpC outer membrane porin protein genes of
RT   lambdoid bacteriophage.";
RL   J. Biol. Chem. 261:12723-12732(1986).
CC   -!- FUNCTION: Forms pores that allow passive diffusion of small molecules
CC       across the host cell outer membrane.
CC   -!- SUBUNIT: Homotrimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cell outer membrane {ECO:0000250}; Multi-
CC       pass membrane protein {ECO:0000250}.
CC   -!- MISCELLANEOUS: A porin gene can also be found in the genomes of certain
CC       lambdoid bacteriophage, and its protein is expressed in the lysogenic
CC       state. In E.coli the expression of ompC and ompF proteins is then
CC       reduced substantially.
CC   -!- SIMILARITY: Belongs to the Gram-negative porin family. {ECO:0000305}.
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DR   EMBL; J02580; AAA32301.1; -; Genomic_DNA.
DR   PIR; D25647; MMBPP2.
DR   SMR; P07238; -.
DR   TCDB; 1.B.1.1.5; the general bacterial porin (gbp) family.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; IEA:InterPro.
DR   CDD; cd00342; gram_neg_porins; 1.
DR   Gene3D; 2.40.160.10; -; 1.
DR   InterPro; IPR033900; Gram_neg_porin_domain.
DR   InterPro; IPR023614; Porin_dom_sf.
DR   InterPro; IPR001897; Porin_gammaproteobac.
DR   InterPro; IPR001702; Porin_Gram-ve.
DR   InterPro; IPR013793; Porin_Gram-ve_CS.
DR   Pfam; PF00267; Porin_1; 1.
DR   PRINTS; PR00183; ECOLIPORIN.
DR   PRINTS; PR00182; ECOLNEIPORIN.
DR   PROSITE; PS00576; GRAM_NEG_PORIN; 1.
PE   3: Inferred from homology;
KW   Host cell outer membrane; Host membrane; Ion transport; Membrane; Porin;
KW   Signal; Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..23
FT   CHAIN           24..365
FT                   /note="Outer membrane porin protein LC"
FT                   /id="PRO_0000025253"
SQ   SEQUENCE   365 AA;  40290 MW;  0FBC0531FB9C0205 CRC64;
     MKKLTVAISA VAASVLMAMS AQAAEIYNKD SNKLDLYGKV NAKHYFSSND ADDGDTTYAR
     LGFKGETQIN DQLTGFGQWE YEFKGNRAES QGSSKDKTHL AFAGLKFGDY GSIDYGRNYG
     VAYDIGAWTD VLPEFGGDTW TQTDVFMTGR TTGFATYRNN DFFGLVDGLN FAAQYQGKND
     RSDFDNYTEG NGDGFGFSAT YEYEGFGIGA TYAKSDRTDT QVNAGKVLPE VFASGKNAEV
     WAAGLKYDAN NIYLATTYSE TQNMTVFADH FVANKAQNFE AVAQYQFDFG LRPSVAYLQS
     KGKDLGVWGD QDLVKYVDVG ATYYFNKNMS TFVDYKINLL DKNDFTKALG VSTDDIVAVG
     LVYQF