PORI_RHOCA
ID PORI_RHOCA Reviewed; 301 AA.
AC P31243;
DT 01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1993, sequence version 1.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=Porin;
OS Rhodobacter capsulatus (Rhodopseudomonas capsulata).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC Rhodobacteraceae; Rhodobacter.
OX NCBI_TaxID=1061;
RN [1]
RP PROTEIN SEQUENCE.
RC STRAIN=DSM 938 / 37b4;
RX PubMed=1651239; DOI=10.1111/j.1432-1033.1991.tb16158.x;
RA Schiltz E., Kreusch A., Nestel U., Schulz G.E.;
RT "Primary structure of porin from Rhodobacter capsulatus.";
RL Eur. J. Biochem. 199:587-594(1991).
RN [2]
RP X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS).
RC STRAIN=DSM 938 / 37b4;
RX PubMed=2165921; DOI=10.1016/0014-5793(90)80942-c;
RA Weiss M.S., Wacker T., Weckesser J., Welte W., Schulz G.E.;
RT "The three-dimensional structure of porin from Rhodobacter capsulatus at 3-
RT A resolution.";
RL FEBS Lett. 267:268-272(1990).
RN [3]
RP X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS).
RC STRAIN=DSM 938 / 37b4;
RX PubMed=1707373; DOI=10.1016/0014-5793(91)80336-2;
RA Weiss M.S., Kreusch A., Schiltz E., Nestel U., Welte W., Weckesser J.,
RA Schulz G.E.;
RT "The structure of porin from Rhodobacter capsulatus at 1.8-A resolution.";
RL FEBS Lett. 280:379-382(1991).
RN [4]
RP X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS).
RX PubMed=1328651; DOI=10.1016/0022-2836(92)90903-w;
RA Weiss M.S., Schulz G.E.;
RT "Structure of porin refined at 1.8-A resolution.";
RL J. Mol. Biol. 227:493-509(1992).
CC -!- FUNCTION: Forms channels that allow the passive diffusion of small
CC hydrophilic solutes up to an exclusion limit of about 0.6 kDa.
CC -!- SUBUNIT: Homotrimer.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane; Multi-pass membrane protein.
CC -!- DOMAIN: The monomer consists of a 16-stranded antiparallel beta-pleated
CC sheet barrel (171 residues), three short alpha-helices (18 residues)
CC and 13 hydrogen-bonded reverse turns (26 residues).
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DR PIR; S16070; S16070.
DR PDB; 2POR; X-ray; 1.80 A; A=1-301.
DR PDB; 3POR; X-ray; 2.50 A; A=1-301.
DR PDBsum; 2POR; -.
DR PDBsum; 3POR; -.
DR AlphaFoldDB; P31243; -.
DR SMR; P31243; -.
DR DrugBank; DB04233; (Hydroxyethyloxy)Tri(Ethyloxy)Octane.
DR EvolutionaryTrace; P31243; -.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR Gene3D; 2.40.160.10; -; 1.
DR InterPro; IPR033900; Gram_neg_porin_domain.
DR InterPro; IPR023614; Porin_dom_sf.
DR Pfam; PF13609; Porin_4; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cell outer membrane; Direct protein sequencing;
KW Ion transport; Membrane; Porin; Transmembrane; Transmembrane beta strand;
KW Transport.
FT CHAIN 1..301
FT /note="Porin"
FT /id="PRO_0000198028"
FT STRAND 2..14
FT /evidence="ECO:0007829|PDB:2POR"
FT STRAND 19..34
FT /evidence="ECO:0007829|PDB:2POR"
FT STRAND 40..46
FT /evidence="ECO:0007829|PDB:2POR"
FT HELIX 47..49
FT /evidence="ECO:0007829|PDB:2POR"
FT HELIX 50..53
FT /evidence="ECO:0007829|PDB:2POR"
FT TURN 54..56
FT /evidence="ECO:0007829|PDB:2POR"
FT STRAND 57..65
FT /evidence="ECO:0007829|PDB:2POR"
FT STRAND 68..74
FT /evidence="ECO:0007829|PDB:2POR"
FT HELIX 78..83
FT /evidence="ECO:0007829|PDB:2POR"
FT TURN 90..93
FT /evidence="ECO:0007829|PDB:2POR"
FT STRAND 105..107
FT /evidence="ECO:0007829|PDB:2POR"
FT HELIX 113..115
FT /evidence="ECO:0007829|PDB:3POR"
FT STRAND 118..125
FT /evidence="ECO:0007829|PDB:2POR"
FT STRAND 128..134
FT /evidence="ECO:0007829|PDB:2POR"
FT STRAND 137..139
FT /evidence="ECO:0007829|PDB:2POR"
FT STRAND 148..158
FT /evidence="ECO:0007829|PDB:2POR"
FT STRAND 161..171
FT /evidence="ECO:0007829|PDB:2POR"
FT TURN 175..177
FT /evidence="ECO:0007829|PDB:2POR"
FT STRAND 181..192
FT /evidence="ECO:0007829|PDB:2POR"
FT STRAND 195..207
FT /evidence="ECO:0007829|PDB:2POR"
FT HELIX 208..214
FT /evidence="ECO:0007829|PDB:2POR"
FT STRAND 221..223
FT /evidence="ECO:0007829|PDB:3POR"
FT STRAND 226..240
FT /evidence="ECO:0007829|PDB:2POR"
FT STRAND 243..254
FT /evidence="ECO:0007829|PDB:2POR"
FT TURN 255..257
FT /evidence="ECO:0007829|PDB:2POR"
FT STRAND 258..272
FT /evidence="ECO:0007829|PDB:2POR"
FT STRAND 275..284
FT /evidence="ECO:0007829|PDB:2POR"
FT STRAND 286..288
FT /evidence="ECO:0007829|PDB:2POR"
FT STRAND 292..301
FT /evidence="ECO:0007829|PDB:2POR"
SQ SEQUENCE 301 AA; 31537 MW; 4C57149C348D2943 CRC64;
EVKLSGDARM GVMYNGDDWN FSSRSRVLFT MSGTTDSGLE FGASFKAHES VGAETGEDGT
VFLSGAFGKI EMGDALGASE ALFGDLYEVG YTDLDDRGGN DIPYLTGDER LTAEDNPVLL
YTYSAGAFSV AASMSDGKVG ETSEDDAQEM AVAAAYTFGN YTVGLGYEKI DSPDTALMAD
MEQLELAAIA KFGATNVKAY YADGELDRDF ARAVFDLTPV AAAATAVDHK AYGLSVDSTF
GATTVGGYVQ VLDIDTIDDV TYYGLGASYD LGGGASIVGG IADNDLPNSD MVADLGVKFK
F
