PORTL_BPHC1
ID PORTL_BPHC1 Reviewed; 345 AA.
AC P51717;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 02-DEC-2020, entry version 76.
DE RecName: Full=Probable portal protein;
DE AltName: Full=ORF15;
OS Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1).
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Caudovirales; Myoviridae; Peduovirinae; Hpunavirus.
OX NCBI_TaxID=1289570;
OH NCBI_TaxID=727; Haemophilus influenzae.
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=8710508; DOI=10.1093/nar/24.12.2360;
RA Esposito D., Fitzmaurice W.P., Benjamin R.C., Goodman S.D., Waldman A.S.,
RA Scocca J.J.;
RT "The complete nucleotide sequence of bacteriophage HP1 DNA.";
RL Nucleic Acids Res. 24:2360-2368(1996).
CC -!- FUNCTION: Forms the portal vertex of the capsid. This portal plays
CC critical roles in head assembly, genome packaging, neck/tail
CC attachment, and genome ejection. The portal protein multimerizes as a
CC single ring-shaped homododecamer arranged around a central channel.
CC Binds to the terminase subunits to form the packaging machine.
CC {ECO:0000250|UniProtKB:P25480}.
CC -!- SUBUNIT: Homododecamer. {ECO:0000250|UniProtKB:P25480}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:P25480}.
CC -!- SIMILARITY: Belongs to the phage portal family. PBSX subfamily.
CC {ECO:0000305}.
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DR EMBL; U24159; AAB09200.1; -; Genomic_DNA.
DR PIR; S69521; S69521.
DR RefSeq; NP_043484.1; NC_001697.1.
DR GeneID; 1261113; -.
DR KEGG; vg:1261113; -.
DR Proteomes; UP000001713; Genome.
DR GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR GO; GO:0099000; P:viral genome ejection through host cell envelope, contractile tail mechanism; IEA:UniProtKB-KW.
DR InterPro; IPR030935; PBSX_Proteobac.
DR InterPro; IPR006944; Phage/GTA_portal.
DR InterPro; IPR006430; Phage_portal_PBSX.
DR Pfam; PF04860; Phage_portal; 1.
DR PIRSF; PIRSF018494; PBSX_VPQ; 1.
DR TIGRFAMs; TIGR01540; portal_PBSX; 1.
PE 3: Inferred from homology;
KW Capsid protein; Reference proteome; Viral capsid assembly;
KW Viral contractile tail ejection system;
KW Viral genome ejection through host cell envelope; Viral genome packaging;
KW Viral penetration into host cytoplasm; Viral release from host cell;
KW Virion; Virus entry into host cell.
FT CHAIN 1..345
FT /note="Probable portal protein"
FT /id="PRO_0000165314"
SQ SEQUENCE 345 AA; 38480 MW; 7F0585CE1AAB7245 CRC64;
MKTNVKTDNK KGIVIAPIND RTFSLSEITA SPALDYVGIG FDENYNCYLP PVNRHALAKL
PHQNAQHGGI LHSRANMVSA TYEGGKALSK MEMRALCLNL IQFGDVGLLK VRNGFGQVVR
LVPLSSLYLR VHKDGGYSYL MKKSLYDTAQ EIYRYDAKDI IFIKLYDPMQ QVYGSPDYVG
GIQSALLNSD ATVFRRRYFS NGAHMGFILY STDPDLTEEM EEEIARKISE SKGVGNFRSM
FVNIAGGHPD GLKVIPIGDT GTKDEFANIK NISAQDVLTA HRFPAGLSGI IPTNTGGLGD
PLKYREVYHY DEVMPLQEII AETINQDPEI KNLLKIKFRE QNFAK