ID   PORTL_BPMD2             Reviewed;         485 AA.
AC   O64207;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   02-JUN-2021, entry version 51.
DE   RecName: Full=Portal protein {ECO:0000305};
DE   AltName: Full=Gene product 14;
DE            Short=gp14;
DE   AltName: Full=Portal vertex protein {ECO:0000305};
GN   Name=14;
OS   Mycobacterium phage D29 (Mycobacteriophage D29).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae; Fromanvirus.
OX   NCBI_TaxID=28369;
OH   NCBI_TaxID=1763; Mycobacterium.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=9636706; DOI=10.1006/jmbi.1997.1610;
RA   Ford M.E., Sarkis G.J., Belanger A.E., Hendrix R.W., Hatfull G.F.;
RT   "Genome structure of mycobacteriophage D29: implications for phage
RT   evolution.";
RL   J. Mol. Biol. 279:143-164(1998).
CC   -!- FUNCTION: Forms the portal vertex of the capsid. This portal plays
CC       critical roles in head assembly, genome packaging, neck/tail
CC       attachment, and genome ejection. The portal protein multimerizes as a
CC       single ring-shaped homododecamer arranged around a central channel.
CC       Binds to the terminase subunits to form the packaging machine.
CC       {ECO:0000250|UniProtKB:P54309}.
CC   -!- SUBUNIT: Homododecamer. {ECO:0000250|UniProtKB:P54309}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:P03710}.
CC   -!- SIMILARITY: Belongs to the SPP1-like portal protein family.
CC       {ECO:0000305}.
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DR   EMBL; AF022214; AAC18454.1; -; Genomic_DNA.
DR   PIR; C72801; C72801.
DR   RefSeq; NP_046829.1; NC_001900.1.
DR   GeneID; 1261620; -.
DR   KEGG; vg:1261620; -.
DR   Proteomes; UP000002131; Genome.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0099001; P:viral genome ejection through host cell envelope, long flexible tail mechanism; IEA:UniProtKB-KW.
DR   InterPro; IPR021145; Portal_protein.
DR   Pfam; PF05133; Phage_prot_Gp6; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Reference proteome; Viral capsid assembly;
KW   Viral genome ejection through host cell envelope; Viral genome packaging;
KW   Viral long flexible tail ejection system;
KW   Viral penetration into host cytoplasm; Viral release from host cell;
KW   Virion; Virus entry into host cell.
FT   CHAIN           1..485
FT                   /note="Portal protein"
FT                   /id="PRO_0000164716"
FT   REGION          456..485
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   485 AA;  53540 MW;  E00EFB1A721789AA CRC64;
     MTAPLPGQEE IADPAIARDE MVSAFEDQNQ NLRSNTSYYE AERRPEAIGV TVPVQMQSLL
     AHVGYPRLYV DSIAERQAVE GFRLGDADEA DEELWQWWQA NNLDIEAPLG YTDAYVHGRS
     YITISRPDPQ IDLGWDPNVP LIRVEPPTRM YAEIDPRIGR PAKAIRVAYD AEGNEIQAAT
     LYTPNETFGW FRAEGEWVEW FSDPHGLGAV PVVPLPNRTR LSDLYGTSEI TPELRSMTDA
     AARILMLMQA TAELMGVPQR LIFGIKPEEI GVDPETGQTL FDAYLARILA FEDAEGKIQQ
     FSAAELANFT NALDQIAKQV AAYTGLPPQY LSTAADNPAS AEAIRAAESR LIKKVERKNA
     IFGGAWEEAM RLAYRLMKGG DVPPDMLRME TVWRDPSTPT YAAKADAATK LYGNGQGVIP
     RERARKDMGY SIAEREEMRR WDEEEAAMGL GLLGTMVDAD PTVPGSPNPT PAPKPQPAIE
     GGDSA