ID   PORTL_BPML5             Reviewed;         486 AA.
AC   Q05220;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   23-FEB-2022, entry version 57.
DE   RecName: Full=Portal protein {ECO:0000305};
DE   AltName: Full=Gene product 14;
DE            Short=gp14;
DE   AltName: Full=Portal vertex protein {ECO:0000305};
GN   Name=14;
OS   Mycobacterium phage L5 (Mycobacteriophage L5).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae; Fromanvirus.
OX   NCBI_TaxID=31757;
OH   NCBI_TaxID=1763; Mycobacterium.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=8459766; DOI=10.1111/j.1365-2958.1993.tb01131.x;
RA   Hatfull G.F., Sarkis G.J.;
RT   "DNA sequence, structure and gene expression of mycobacteriophage L5: a
RT   phage system for mycobacterial genetics.";
RL   Mol. Microbiol. 7:395-405(1993).
CC   -!- FUNCTION: Forms the portal vertex of the capsid. This portal plays
CC       critical roles in head assembly, genome packaging, neck/tail
CC       attachment, and genome ejection. The portal protein multimerizes as a
CC       single ring-shaped homododecamer arranged around a central channel.
CC       Binds to the terminase subunits to form the packaging machine.
CC       {ECO:0000250|UniProtKB:P54309}.
CC   -!- SUBUNIT: Homododecamer. {ECO:0000250|UniProtKB:P54309}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:P03710}.
CC   -!- SIMILARITY: Belongs to the SPP1-like portal protein family.
CC       {ECO:0000305}.
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DR   EMBL; Z18946; CAA79390.1; -; Genomic_DNA.
DR   PIR; S30959; S30959.
DR   RefSeq; NP_039678.1; NC_001335.1.
DR   TCDB; 1.W.7.3.7; the (bacillus phage spp1) portal protein 7 (ppp7) family.
DR   GeneID; 2942930; -.
DR   KEGG; vg:2942930; -.
DR   Proteomes; UP000002123; Genome.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0099001; P:viral genome ejection through host cell envelope, long flexible tail mechanism; IEA:UniProtKB-KW.
DR   InterPro; IPR021145; Portal_protein.
DR   Pfam; PF05133; Phage_prot_Gp6; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Reference proteome; Viral capsid assembly;
KW   Viral genome ejection through host cell envelope; Viral genome packaging;
KW   Viral long flexible tail ejection system;
KW   Viral penetration into host cytoplasm; Viral release from host cell;
KW   Virion; Virus entry into host cell.
FT   CHAIN           1..486
FT                   /note="Portal protein"
FT                   /id="PRO_0000164717"
FT   REGION          456..486
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   486 AA;  53758 MW;  4BF3734A6BB11BF5 CRC64;
     MTAPLPGMEE IEDPAVVREE MISAFEDASK DLASNTSYYD AERRPEAIGV TVPREMQQLL
     AHVGYPRLYV DSVAERQAVE GFRLGDADEA DEELWQWWQA NNLDIEAPLG YTDAYVHGRS
     FITISKPDPQ LDLGWDQNVP IIRVEPPTRM HAEIDPRINR VSKAIRVAYD KEGNEIQAAT
     LYTPMETIGW FRADGEWAEW FNVPHGLGVV PVVPLPNRTR LSDLYGTSEI TPELRSMTDA
     AARILMLMQA TAELMGVPQR LIFGIKPEEI GVDSETGQTL FDAYLARILA FEDAEGKIQQ
     FSAAELANFT NALDQIAKQV AAYTGLPPQY LSTAADNPAS AEAIRAAESR LIKKVERKNL
     MFGGAWEEAM RIAYRIMKGG DVPPDMLRME TVWRDPSTPT YAAKADAATK LYGNGQGVIP
     RERARIDMGY SVKEREEMRR WDEEEAAMGL GLLGTMVDAD PTVPGSPSPT APPKPQPAIE
     SSGGDA