ID   PORTL_BPP2              Reviewed;         344 AA.
AC   P25480;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1992, sequence version 1.
DT   23-FEB-2022, entry version 84.
DE   RecName: Full=Probable portal protein;
DE   AltName: Full=GpQ;
GN   Name=Q;
OS   Escherichia phage P2 (Bacteriophage P2).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Peduovirinae; Peduovirus.
OX   NCBI_TaxID=10679;
OH   NCBI_TaxID=543; Enterobacteriaceae.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1837355; DOI=10.1093/nar/19.25.7207;
RA   Linderoth N.A., Ziermann R., Haggaard-Ljungquist E., Christie G.E.,
RA   Calendar R.;
RT   "Nucleotide sequence of the DNA packaging and capsid synthesis genes of
RT   bacteriophage P2.";
RL   Nucleic Acids Res. 19:7207-7214(1991).
RN   [2]
RP   FUNCTION.
RX   PubMed=8178458; DOI=10.1006/viro.1994.1238;
RA   Rishovd S., Marvik O.J., Jacobsen E., Lindqvist B.H.;
RT   "Bacteriophage P2 and P4 morphogenesis: identification and characterization
RT   of the portal protein.";
RL   Virology 200:744-751(1994).
RN   [3]
RP   SUBUNIT.
RX   PubMed=17049269; DOI=10.1016/j.jsb.2006.08.009;
RA   Doan D.N., Dokland T.;
RT   "The gpQ portal protein of bacteriophage P2 forms dodecameric connectors in
RT   crystals.";
RL   J. Struct. Biol. 157:432-436(2007).
CC   -!- FUNCTION: Forms the portal vertex of the capsid (PubMed:8178458). This
CC       portal plays critical roles in head assembly, genome packaging,
CC       neck/tail attachment, and genome ejection. The portal protein
CC       multimerizes as a single ring-shaped homododecamer arranged around a
CC       central channel. Binds to the terminase subunits to form the packaging
CC       machine. {ECO:0000269|PubMed:8178458, ECO:0000305}.
CC   -!- SUBUNIT: Homododecamer. {ECO:0000269|PubMed:17049269}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the phage portal family. PBSX subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AF063097; AAD03268.1; -; Genomic_DNA.
DR   PIR; S22796; S22796.
DR   RefSeq; NP_046757.1; NC_001895.1.
DR   SMR; P25480; -.
DR   TCDB; 1.W.3.1.1; the phage portal protein 3 (ppp3) family.
DR   GeneID; 1261529; -.
DR   KEGG; vg:1261529; -.
DR   Proteomes; UP000009092; Genome.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0099000; P:viral genome ejection through host cell envelope, contractile tail mechanism; IEA:UniProtKB-KW.
DR   InterPro; IPR030935; PBSX_Proteobac.
DR   InterPro; IPR006944; Phage/GTA_portal.
DR   InterPro; IPR006430; Phage_portal_PBSX.
DR   Pfam; PF04860; Phage_portal; 1.
DR   PIRSF; PIRSF018494; PBSX_VPQ; 1.
DR   TIGRFAMs; TIGR01540; portal_PBSX; 1.
PE   1: Evidence at protein level;
KW   Capsid protein; Reference proteome; Viral capsid assembly;
KW   Viral contractile tail ejection system;
KW   Viral genome ejection through host cell envelope; Viral genome packaging;
KW   Viral penetration into host cytoplasm; Viral release from host cell;
KW   Virion; Virus entry into host cell.
FT   CHAIN           1..344
FT                   /note="Probable portal protein"
FT                   /id="PRO_0000165260"
SQ   SEQUENCE   344 AA;  39115 MW;  FAD61987530029A7 CRC64;
     MSKKKGKTPQ PAAKTMTASG PKMEAFTFGE PVPVLDRRDI LDYVECISNG RWYEPPVSFT
     GLAKSLRAAV HHSSPIYVKR NILASTFIPH PWLSQQDFSR FVLDFLVFGN AFLEKRYSTT
     GKVIRLETSP AKYTRRGVEE DVYWWVPSFN EPTAFAPGSV FHLLEPDINQ ELYGLPEYLS
     ALNSAWLNES ATLFRRKYYE NGAHAGYIMY VTDAVQDRND IEMLRENMVK SKGRNNFKNL
     FLYAPQGKAD GIKIIPLSEV ATKDDFFNIK KASAADLLDA HRIPFQLMGG KPENVGSLGD
     IEKVAKVFVR NELIPLQDRI REINGWLGQE VIRFKNYSLD TDND