ID   PORTL_BPPCD             Reviewed;         451 AA.
AC   Q24LJ4;
DT   01-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2006, sequence version 1.
DT   23-FEB-2022, entry version 47.
DE   RecName: Full=Portal protein;
DE   AltName: Full=Portal vertex protein;
OS   Clostridium phage phiCD119 (strain Clostridium difficile/United
OS   States/Govind/2006) (Bacteriophage phiCD119).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Lubbockvirus.
OX   NCBI_TaxID=1283341;
OH   NCBI_TaxID=1496; Clostridioides difficile (Peptoclostridium difficile).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16547044; DOI=10.1128/jb.188.7.2568-2577.2006;
RA   Govind R., Fralick J.A., Rolfe R.D.;
RT   "Genomic organization and molecular characterization of Clostridium
RT   difficile bacteriophage PhiCD119.";
RL   J. Bacteriol. 188:2568-2577(2006).
CC   -!- FUNCTION: Forms the portal vertex of the capsid. This portal plays
CC       critical roles in head assembly, genome packaging, neck/tail
CC       attachment, and genome ejection. The portal protein multimerizes as a
CC       single ring-shaped homododecamer arranged around a central channel.
CC       Binds to the terminase subunits to form the packaging machine.
CC       {ECO:0000250|UniProtKB:P54309}.
CC   -!- SUBUNIT: Homododecamer. {ECO:0000250|UniProtKB:P54309}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:P03710}.
CC   -!- SIMILARITY: Belongs to the SPP1-like portal protein family.
CC       {ECO:0000305}.
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DR   EMBL; AY855346; AAZ32264.1; -; Genomic_DNA.
DR   RefSeq; YP_529555.1; NC_007917.1.
DR   SMR; Q24LJ4; -.
DR   GeneID; 3974462; -.
DR   KEGG; vg:3974462; -.
DR   Proteomes; UP000006649; Genome.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0099000; P:viral genome ejection through host cell envelope, contractile tail mechanism; IEA:UniProtKB-KW.
DR   InterPro; IPR021145; Portal_protein.
DR   InterPro; IPR006428; Portal_SPP1-type.
DR   Pfam; PF05133; Phage_prot_Gp6; 1.
DR   TIGRFAMs; TIGR01538; portal_SPP1; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Reference proteome; Viral capsid assembly;
KW   Viral contractile tail ejection system;
KW   Viral genome ejection through host cell envelope; Viral genome packaging;
KW   Viral penetration into host cytoplasm; Viral release from host cell;
KW   Virion; Virus entry into host cell.
FT   CHAIN           1..451
FT                   /note="Portal protein"
FT                   /id="PRO_0000432535"
SQ   SEQUENCE   451 AA;  52525 MW;  5162F3977519EB8B CRC64;
     MELEKIRAII SADAARRQEI LQAKSYYYNK NDILKKGVVV QNRDENPLRN ADNRISHNFH
     EILVDEKASY MFTYPVLFDI DNNKELNEKV TDVLGNEFTR KAKNLAIEAS NCGSAWLHYW
     IDEEYSGEQV TNQTFKYGVV NTEEIIPIYR NGIERELEAV IRYYIQLEDV KGQIQKQAYT
     YVEFWTDKIL DKYKFFGVSC CGSQIEHITV QHRFNSVPFV EFSNNIKKQS DLSKYKKILD
     LYDRVMSGFA NDLEDIQQII YILENFGGED TSEFLKELKR YKTIKTETDS EGDSGGLKTM
     QIEIPTEARK IILEILKKQI YESGQGLQQD TENFGNASGV ALKFFYRKLE LKSGLLETEF
     RTSFDKLIKA ILYFLGVTDY KKIQQTYTRN MMSNDLEDAD IATKSVGIIP TKIILRHHPW
     VDDVEEAEKL YLEEKKIQAS KVSDDYNNFT E