PORTL_BPPHC
ID PORTL_BPPHC Reviewed; 457 AA.
AC Q9ZXB2;
DT 01-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 65.
DE RecName: Full=Probable portal protein;
GN Name=34 {ECO:0000312|EMBL:CAA07104.1};
OS Streptomyces phage phiC31 (Bacteriophage phi-C31).
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Caudovirales; Siphoviridae; Lomovskayavirus.
OX NCBI_TaxID=10719 {ECO:0000312|Proteomes:UP000002124};
OH NCBI_TaxID=1902; Streptomyces coelicolor.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Norwich {ECO:0000312|Proteomes:UP000002124};
RX PubMed=10219087; DOI=10.1093/nar/27.10.2145;
RA Smith M.C., Burns R.N., Wilson S.E., Gregory M.A.;
RT "The complete genome sequence of the Streptomyces temperate phage straight
RT phiC31: evolutionary relationships to other viruses.";
RL Nucleic Acids Res. 27:2145-2155(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Norwich {ECO:0000312|Proteomes:UP000002124};
RX PubMed=10051617; DOI=10.1073/pnas.96.5.2192;
RA Hendrix R.W., Smith M.C.M., Burns N., Ford M.E., Hatfull G.F.;
RT "Evolutionary relationships among diverse bacteriophages and prophages: all
RT the world's a phage.";
RL Proc. Natl. Acad. Sci. U.S.A. 96:2192-2197(1999).
CC -!- FUNCTION: Forms the portal vertex of the capsid. This portal plays
CC critical roles in head assembly, genome packaging, neck/tail
CC attachment, and genome ejection. The portal protein multimerizes as a
CC single ring-shaped homododecamer arranged around a central channel.
CC Binds to the terminase subunits to form the packaging machine.
CC {ECO:0000250|UniProtKB:P25480}.
CC -!- SUBUNIT: Homododecamer. {ECO:0000250|UniProtKB:P25480}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:P25480}.
CC -!- SIMILARITY: Belongs to the phage portal family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJ006589; CAA07104.1; -; Genomic_DNA.
DR RefSeq; NP_047925.1; NC_001978.3.
DR SMR; Q9ZXB2; -.
DR GeneID; 2715872; -.
DR KEGG; vg:2715872; -.
DR Proteomes; UP000002124; Genome.
DR GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR GO; GO:0099001; P:viral genome ejection through host cell envelope, long flexible tail mechanism; IEA:UniProtKB-KW.
DR InterPro; IPR006944; Phage/GTA_portal.
DR InterPro; IPR006427; Portal_HK97.
DR Pfam; PF04860; Phage_portal; 1.
DR TIGRFAMs; TIGR01537; portal_HK97; 1.
PE 3: Inferred from homology;
KW Capsid protein; DNA-binding; Hydrolase; Protease; Reference proteome;
KW Viral capsid assembly; Viral genome ejection through host cell envelope;
KW Viral genome packaging; Viral long flexible tail ejection system;
KW Viral penetration into host cytoplasm; Viral release from host cell;
KW Virion; Virus entry into host cell.
FT CHAIN 1..457
FT /note="Probable portal protein"
FT /id="PRO_0000432536"
FT REGION 391..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..457
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 457 AA; 49842 MW; 5CBC9042D2D0594A CRC64;
MGFWSALFGR GHSPALDGIE ARAWEPYDPS IYNLGAVAAS GETVTPHDAL QVSAVFASVR
LLSETIATLP LSTYSKRGGS RKEIVTPEWL DYPNAEPGGM GRIDILSQTV LSLLLQGNAF
LAVRWQGPNI VGLDVLDPTK IHVHMVMVDG LRRKVFEAYD IDADGNEVLL GWFTPRDVLH
IPGMMLPGDF VGCSPISYAR ESIGLALAAQ KYGSKFFANG AMPGAVVEVP GTMSEEGLAR
AREAWRAANS GVDNAHRVAL LTEGAKFSKV AMSPDEAQFL QTRQFQVPEI ARIFGVPPHL
ISDATNSTSW GSGLAEQNIA FTMFSLRPWL ERIEAGFNRL LFAETADRFR FVKFNLDEIK
RGAPKERMEL WSLGLQNGIY SIDEVRAAED MTPLPDGLGE KYRVPLNLGE VGEEPEPEPA
PAPPAIEPPA EEPDEEPEPE GKPDDEGATE EDDEDDA
