ID   PORTL_EBVA8             Reviewed;         613 AA.
AC   Q1HVF2;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   13-JUN-2006, sequence version 1.
DT   03-AUG-2022, entry version 50.
DE   RecName: Full=Portal protein {ECO:0000255|HAMAP-Rule:MF_04012};
GN   ORFNames=BBRF1;
OS   Epstein-Barr virus (strain AG876) (HHV-4) (Human herpesvirus 4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Lymphocryptovirus.
OX   NCBI_TaxID=82830;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16490228; DOI=10.1016/j.virol.2006.01.015;
RA   Dolan A., Addison C., Gatherer D., Davison A.J., McGeoch D.J.;
RT   "The genome of Epstein-Barr virus type 2 strain AG876.";
RL   Virology 350:164-170(2006).
CC   -!- FUNCTION: Forms a portal in the viral capsid through which viral DNA is
CC       translocated during DNA packaging. Assembles as a dodecamer at a single
CC       fivefold axe of the T=16 icosahedric capsid. Binds to the molecular
CC       motor that translocates the viral DNA, termed terminase.
CC       {ECO:0000255|HAMAP-Rule:MF_04012}.
CC   -!- SUBUNIT: Homododecamerizes. Interacts with terminase subunits TRM1 and
CC       TRM3. {ECO:0000255|HAMAP-Rule:MF_04012}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000255|HAMAP-Rule:MF_04012}. Host
CC       nucleus {ECO:0000255|HAMAP-Rule:MF_04012}.
CC   -!- SIMILARITY: Belongs to the herpesviridae portal protein family.
CC       {ECO:0000255|HAMAP-Rule:MF_04012}.
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DR   EMBL; DQ279927; ABB89256.1; -; Genomic_DNA.
DR   RefSeq; YP_001129476.1; NC_009334.1.
DR   SMR; Q1HVF2; -.
DR   PRIDE; Q1HVF2; -.
DR   GeneID; 5176175; -.
DR   KEGG; vg:5176175; -.
DR   Proteomes; UP000007639; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0044423; C:virion component; IEA:UniProtKB-UniRule.
DR   GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR   GO; GO:0019076; P:viral release from host cell; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_04012; HSV_PORTL; 1.
DR   InterPro; IPR002660; Herpes_Portal.
DR   Pfam; PF01763; Herpes_UL6; 1.
PE   3: Inferred from homology;
KW   Host nucleus; Reference proteome; Viral genome packaging;
KW   Viral release from host cell; Virion.
FT   CHAIN           1..613
FT                   /note="Portal protein"
FT                   /id="PRO_0000375974"
FT   REGION          577..613
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   613 AA;  68356 MW;  71D71481884B8B38 CRC64;
     MFNMNVDESA SGALGSSAIP VHPTPASVRL FEILQGKYAY VQGQTIYANL RNPGVFSRQV
     FTHLFKRAIS HCTYDDVLHD WNKFEACIQK RWPSDDSCAS RFRESTFESW STTMKLTVRD
     LLTTNIYRVL HSRSVLSYER YVDWICATGM VPAVKKPITQ ELHSKIKSLR DRCVCRELGH
     ERTIRSIGTE LYEATREIIE SLNSTFIPQF TEVTIEYLPG SDEYVAYYCG RRIRLHVLFP
     PAIFAGTVTF DSPVQRLYQN IFMCYRTLEH AKICQLLNTA PLKAIVGHGG RDMYKDILAH
     LEQNSQRKDP KKELLNLLVK LSENKTISGV TDVVEEFITD ASNNLVDRNR LFGQPGETAA
     QGLKKKVSNT VVKCLTDQIN EQFDQINGLE KERELYLKKI RSMESQLQAS LGPGGNNPAA
     SAPAAVAAEA ASVDILTGST ASAIEKLFNS PSASLGARVS GHNESILNSF VSQYIPPSRE
     MTKDLTELWE SELFNTFKLT PVVDNQGQRL YVRYSSDTIS ILLGPFTYLV AELSPVELVT
     DVYATLGIVE IIDELYRSSR LAIYIEDLGR KYCPASATGG DHGIRQAPSA RGDAEPDHAK
     SKPARDPPPG AGS