ATA15_ARATH
ID ATA15_ARATH Reviewed; 417 AA.
AC Q9C8Y4; Q5K6K5; Q8LCA3; Q8VZ77;
DT 31-JAN-2018, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Senescence-associated protein AAF, chlorolplastic {ECO:0000305};
DE AltName: Full=Protein ARABIDOPSIS A-FIFTEEN {ECO:0000303|PubMed:21940719};
DE Flags: Precursor;
GN Name=AAF {ECO:0000303|PubMed:21940719};
GN Synonyms=ATA15 {ECO:0000303|PubMed:12650614};
GN OrderedLocusNames=At1g66330 {ECO:0000312|Araport:AT1G66330};
GN ORFNames=T27F4.8 {ECO:0000312|EMBL:AAG52167.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RC STRAIN=cv. Columbia; TISSUE=Leaf;
RX PubMed=12650614; DOI=10.1023/a:1022334820332;
RA Yap M.N., Lee R.H., Huang Y.J., Liao C.J., Chen S.C.;
RT "Molecular characterization of a novel senescence-associated gene SPA15
RT induced during leaf senescence in sweet potato.";
RL Plant Mol. Biol. 51:471-481(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 218-417.
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [6]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE,
RP INDUCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=21940719; DOI=10.1093/jxb/err278;
RA Chen G.H., Liu C.P., Chen S.C., Wang L.C.;
RT "Role of ARABIDOPSIS A-FIFTEEN in regulating leaf senescence involves
RT response to reactive oxygen species and is dependent on ETHYLENE
RT INSENSITIVE2.";
RL J. Exp. Bot. 63:275-292(2012).
CC -!- FUNCTION: Involved in modulation of redox homeostasis to regulate leaf
CC senescence mediated by age and stress factors during plant development.
CC Its function is dependent of EIN2, a central factor of ethylene
CC signaling. {ECO:0000269|PubMed:21940719}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000269|PubMed:21940719}.
CC -!- TISSUE SPECIFICITY: Expressed in leaves (PubMed:12650614). Expressed in
CC 7-day-old seedlings, roots, rosette leaves, cauline leaves and flower
CC buds (PubMed:21940719). {ECO:0000269|PubMed:12650614,
CC ECO:0000269|PubMed:21940719}.
CC -!- DEVELOPMENTAL STAGE: Up-regulated during leaf senescence.
CC {ECO:0000269|PubMed:12650614, ECO:0000269|PubMed:21940719}.
CC -!- INDUCTION: Induced by abscisic acid (ABA), salicylate (SA), methyl
CC jasmonate (MeJA) and ethylene. {ECO:0000269|PubMed:21940719}.
CC -!- DISRUPTION PHENOTYPE: Delayed age-dependent and darkness-induced
CC senescence. Increased resistance to oxidative stress.
CC {ECO:0000269|PubMed:21940719}.
CC -!- MISCELLANEOUS: Plants overexpressing AAF exhibit increased root growth,
CC elevated level of cellular reactive oxygen species (ROS), enhanced
CC sensitivity to oxidative stress, and early leaf senescence induced by
CC continuous darkness and by age-dependent signaling.
CC {ECO:0000269|PubMed:21940719}.
CC -!- SIMILARITY: Belongs to the ATA15/OSA15 family.
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DR EMBL; AF359253; AAQ15186.1; -; mRNA.
DR EMBL; AC020665; AAG52167.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34495.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34496.1; -; Genomic_DNA.
DR EMBL; AY086709; AAM63763.1; -; mRNA.
DR EMBL; AY065186; AAL38362.1; -; mRNA.
DR EMBL; AY093251; AAM13250.1; -; mRNA.
DR PIR; E96688; E96688.
DR RefSeq; NP_564872.1; NM_105304.2.
DR RefSeq; NP_974095.1; NM_202366.3.
DR AlphaFoldDB; Q9C8Y4; -.
DR SMR; Q9C8Y4; -.
DR STRING; 3702.AT1G66330.2; -.
DR iPTMnet; Q9C8Y4; -.
DR PaxDb; Q9C8Y4; -.
DR PRIDE; Q9C8Y4; -.
DR ProteomicsDB; 246528; -.
DR EnsemblPlants; AT1G66330.1; AT1G66330.1; AT1G66330.
DR EnsemblPlants; AT1G66330.2; AT1G66330.2; AT1G66330.
DR GeneID; 842950; -.
DR Gramene; AT1G66330.1; AT1G66330.1; AT1G66330.
DR Gramene; AT1G66330.2; AT1G66330.2; AT1G66330.
DR KEGG; ath:AT1G66330; -.
DR Araport; AT1G66330; -.
DR TAIR; locus:2201547; AT1G66330.
DR eggNOG; ENOG502QPKY; Eukaryota.
DR HOGENOM; CLU_048664_0_0_1; -.
DR InParanoid; Q9C8Y4; -.
DR OMA; DIHDMMV; -.
DR OrthoDB; 800616at2759; -.
DR PhylomeDB; Q9C8Y4; -.
DR PRO; PR:Q9C8Y4; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C8Y4; baseline and differential.
DR GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR GO; GO:0034599; P:cellular response to oxidative stress; IMP:TAIR.
DR GO; GO:0010150; P:leaf senescence; IMP:TAIR.
DR GO; GO:0072593; P:reactive oxygen species metabolic process; IMP:TAIR.
DR GO; GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR.
DR InterPro; IPR044973; AAF-like.
DR PANTHER; PTHR36725; PTHR36725; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Plastid; Reference proteome; Transit peptide.
FT TRANSIT 1..36
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 37..417
FT /note="Senescence-associated protein AAF, chlorolplastic"
FT /id="PRO_0000443063"
FT CONFLICT 44
FT /note="I -> V (in Ref. 4; AAM63763)"
FT /evidence="ECO:0000305"
FT CONFLICT 59
FT /note="F -> L (in Ref. 4; AAM63763)"
FT /evidence="ECO:0000305"
FT CONFLICT 74
FT /note="S -> P (in Ref. 1; AAQ15186)"
FT /evidence="ECO:0000305"
FT CONFLICT 116
FT /note="V -> A (in Ref. 1; AAQ15186)"
FT /evidence="ECO:0000305"
FT CONFLICT 181
FT /note="F -> L (in Ref. 4; AAM63763)"
FT /evidence="ECO:0000305"
FT CONFLICT 222
FT /note="L -> F (in Ref. 4; AAM63763)"
FT /evidence="ECO:0000305"
FT CONFLICT 240..244
FT /note="VDSLV -> LDSLL (in Ref. 4; AAM63763)"
FT /evidence="ECO:0000305"
FT CONFLICT 403
FT /note="R -> T (in Ref. 4; AAM63763)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 417 AA; 45861 MW; CA0EF94B35D3E78D CRC64;
MALNVSKVVP NSPILVKSVN ASRSRRVLLA YVHHPLAANK GSSIEELKQG LCCTKTVTFV
SSRRCSTLCF VGKSQDTETN SQVVQKEGEK QVMPRRKSSN SSQLLVEYVS NDAKFVNERA
RNDFVLLSRG IMRLDARARQ DVAILGSGFL KLDARAREDT EKIDRDVKRK AERLHHIATI
FKNIAESKLK NAADKHWSDG ALEADLRRAD FRAKQRAMED ALMALEFIKN IHDMMVNKMV
DSLVTSETGT TDRISLEKNG IALGFFPGEV SSDRISAIEE AYKSMASALS EADGIDYTDP
EELELLVTTL IDLDAMDGKS SASLLAECSS SPDVNTRKAL ANALAAAPSM WTLGNAGMGA
LQRLAEDSNP AIAAAASRAI NALKKQWEVE EGDSLRFMMN FERPNDDDDV DSDLDEI
