ID   PORTL_EHV2              Reviewed;         598 AA.
AC   Q66646;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Portal protein {ECO:0000255|HAMAP-Rule:MF_04012};
GN   Name=43;
OS   Equine herpesvirus 2 (strain 86/87) (EHV-2).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Percavirus.
OX   NCBI_TaxID=82831;
OH   NCBI_TaxID=9796; Equus caballus (Horse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=7783207; DOI=10.1006/jmbi.1995.0314;
RA   Telford E.A.R., Watson M.S., Aird H.C., Perry J., Davison A.J.;
RT   "The DNA sequence of equine herpesvirus 2.";
RL   J. Mol. Biol. 249:520-528(1995).
CC   -!- FUNCTION: Forms a portal in the viral capsid through which viral DNA is
CC       translocated during DNA packaging. Assembles as a dodecamer at a single
CC       fivefold axe of the T=16 icosahedric capsid. Binds to the molecular
CC       motor that translocates the viral DNA, termed terminase.
CC       {ECO:0000255|HAMAP-Rule:MF_04012}.
CC   -!- SUBUNIT: Homododecamerizes. Interacts with terminase subunits TRM1 and
CC       TRM3. {ECO:0000255|HAMAP-Rule:MF_04012}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000255|HAMAP-Rule:MF_04012}. Host
CC       nucleus {ECO:0000255|HAMAP-Rule:MF_04012}.
CC   -!- SIMILARITY: Belongs to the herpesviridae portal protein family.
CC       {ECO:0000255|HAMAP-Rule:MF_04012}.
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DR   EMBL; U20824; AAC13831.1; -; Genomic_DNA.
DR   PIR; S55638; S55638.
DR   RefSeq; NP_042640.1; NC_001650.2.
DR   SMR; Q66646; -.
DR   GeneID; 1461078; -.
DR   KEGG; vg:1461078; -.
DR   Proteomes; UP000007083; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0044423; C:virion component; IEA:UniProtKB-UniRule.
DR   GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR   GO; GO:0019076; P:viral release from host cell; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_04012; HSV_PORTL; 1.
DR   InterPro; IPR002660; Herpes_Portal.
DR   Pfam; PF01763; Herpes_UL6; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Host nucleus; Reference proteome; Viral genome packaging;
KW   Viral release from host cell; Virion.
FT   CHAIN           1..598
FT                   /note="Portal protein"
FT                   /id="PRO_0000406034"
SQ   SEQUENCE   598 AA;  67204 MW;  D44F1CE9A28F0904 CRC64;
     MNPAPGSSII MIHPSRFSVP LFEILQGKYS YVKGQTLHSS LRNPGVFSRQ LFVHLYKRAL
     SRCTYDEVLS DWQLFEAGIR ARWRGSRYES GAFKASTFQS WVDTVKMTLD QLLLNNIYHI
     LHTRTNLSYE RYVDWVVAVG LVPLFVSKPD RALVKSITSK FSADSVGFSS DKYKTMKTVL
     MTFKRELTSV LETVTSIYIP DFSEVQLYFD GSTTAYFGVY RGQRITVEVV NRPIIFNGEV
     TFDSPVQRLF NTVMSCHRTA EHAKLCQLLN TSPMKAVVGS TSNNLYKDIL NHLEQSSHKS
     DPKREMLQLL IKLAENKTVS GITDVVEDFV TDVSQNIVDR NKLFGGGGGG PSAESTAQGL
     KKQVSGTVFK CLTNQINEQF DTIHKLEKER DMMLRKVHTL ETHLSQCRAE DKRLGEVSIT
     SSLLTTDTLK SLLNIHDSSL SLHAASVNKG DNVHNSFFSQ YVPPFREVSQ DLTSLWESEV
     FETFKLTPVI DNQGQRLYVK YSQDTVSVLL GPFTYVITKM YEMELITDVY SSLSLNEIAD
     GLYKSSRLYV YMQDVGAKYN LESQEYFDAA SAASAAAPAA GRTQSPSAFS QQAQHGPP