ATA1_ARATH
ID ATA1_ARATH Reviewed; 272 AA.
AC Q9M1K9; O24452; Q8LDB0;
DT 27-MAY-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Short-chain dehydrogenase reductase ATA1 {ECO:0000305};
DE EC=1.1.1.-;
DE AltName: Full=Protein TAPETUM 1 {ECO:0000303|PubMed:9351239};
DE Short=ATA1 {ECO:0000303|PubMed:9351239};
DE AltName: Full=Tasselseed-2 homolog ATA1 {ECO:0000305};
GN Name=TA1 {ECO:0000305};
GN OrderedLocusNames=At3g42960 {ECO:0000312|Araport:AT3G42960};
GN ORFNames=F18P9.120 {ECO:0000312|EMBL:CAB86683.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP FUNCTION, NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC STRAIN=cv. Columbia;
RX PubMed=9351239; DOI=10.1046/j.1365-313x.1997.00515.x;
RA Lebel-Hardenack S., Ye D., Koutnikova H., Saedler H., Grant S.R.;
RT "Conserved expression of a TASSELSEED2 homolog in the tapetum of the
RT dioecious Silene latifolia and Arabidopsis thaliana.";
RL Plant J. 12:515-526(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May play a role in tapetum development.
CC {ECO:0000305|PubMed:9351239}.
CC -!- INTERACTION:
CC Q9M1K9; Q9M1K9: TA1; NbExp=4; IntAct=EBI-4442798, EBI-4442798;
CC -!- TISSUE SPECIFICITY: Expressed specifically in tapetal cells.
CC {ECO:0000269|PubMed:9351239}.
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000305}.
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DR EMBL; U76501; AAC49835.1; -; mRNA.
DR EMBL; AL138654; CAB86683.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE77761.1; -; Genomic_DNA.
DR EMBL; BT029345; ABK32159.1; -; mRNA.
DR EMBL; AY086103; AAM63311.1; -; mRNA.
DR PIR; T47354; T47354.
DR RefSeq; NP_189882.1; NM_114164.2.
DR AlphaFoldDB; Q9M1K9; -.
DR SMR; Q9M1K9; -.
DR STRING; 3702.AT3G42960.1; -.
DR PaxDb; Q9M1K9; -.
DR PRIDE; Q9M1K9; -.
DR EnsemblPlants; AT3G42960.1; AT3G42960.1; AT3G42960.
DR GeneID; 823352; -.
DR Gramene; AT3G42960.1; AT3G42960.1; AT3G42960.
DR KEGG; ath:AT3G42960; -.
DR Araport; AT3G42960; -.
DR TAIR; locus:2078541; AT3G42960.
DR eggNOG; KOG0725; Eukaryota.
DR HOGENOM; CLU_010194_1_0_1; -.
DR InParanoid; Q9M1K9; -.
DR OMA; MHDLYVD; -.
DR OrthoDB; 1051625at2759; -.
DR PhylomeDB; Q9M1K9; -.
DR BioCyc; ARA:AT3G42960-MON; -.
DR PRO; PR:Q9M1K9; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9M1K9; baseline and differential.
DR Genevisible; Q9M1K9; AT.
DR GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SUPFAM; SSF51735; SSF51735; 1.
PE 1: Evidence at protein level;
KW NADP; Oxidoreductase; Reference proteome.
FT CHAIN 1..272
FT /note="Short-chain dehydrogenase reductase ATA1"
FT /id="PRO_0000433127"
FT ACT_SITE 156
FT /note="Proton acceptor"
FT /evidence="ECO:0000250|UniProtKB:Q8WNV7,
FT ECO:0000255|PROSITE-ProRule:PRU10001"
FT BINDING 14..38
FT /ligand="NADP(+)"
FT /ligand_id="ChEBI:CHEBI:58349"
FT /evidence="ECO:0000250|UniProtKB:Q8WNV7"
FT BINDING 143
FT /ligand="substrate"
FT /evidence="ECO:0000250"
FT BINDING 160
FT /ligand="NADP(+)"
FT /ligand_id="ChEBI:CHEBI:58349"
FT /evidence="ECO:0000250|UniProtKB:Q8WNV7"
FT CONFLICT 44
FT /note="E -> D (in Ref. 1; AAC49835)"
FT /evidence="ECO:0000305"
FT CONFLICT 162
FT /note="A -> G (in Ref. 1; AAC49835)"
FT /evidence="ECO:0000305"
FT CONFLICT 171
FT /note="A -> E (in Ref. 1; AAC49835)"
FT /evidence="ECO:0000305"
FT CONFLICT 204
FT /note="H -> N (in Ref. 5; AAM63311 and 1; AAC49835)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 272 AA; 28346 MW; 304CD9F7CAB16E66 CRC64;
MANSDKRLFE KVAIITGGAR GIGAATARLF TENGAYVIVA DILENEGILV AESIGGCYVH
CDVSKEADVE AAVELAMRRK GRLDVMFNNA GMSLNEGSIM GMDVDMVNKL VSVNVNGVLH
GIKHAAKAMI KGGRGGSIIC TSSSSGLMGG LGGHAYTLSK GAINGVVRTT ACELGSHGIR
VNSISPHGVP TDILVNAYRK FLNHDKLNVA EVTDIIAEKG SLLTGRAGTV EDVAQAALFL
ASQESSGFIT GHNLVVDGGY TSATSTMRFI YN
