ID   POR_LEPBY               Reviewed;         322 AA.
AC   O66148;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 2.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Light-dependent protochlorophyllide reductase;
DE            Short=PCR;
DE            EC=1.3.1.33;
DE   AltName: Full=NADPH-protochlorophyllide oxidoreductase;
DE            Short=LPOR;
DE            Short=POR;
GN   Name=por;
OS   Leptolyngbya boryana (Plectonema boryanum).
OC   Bacteria; Cyanobacteria; Pseudanabaenales; Leptolyngbyaceae; Leptolyngbya.
OX   NCBI_TaxID=1184;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 27894 / CCAP 1463/1 / IAM M-101 / PCC 6306 / UTEX 581;
RX   PubMed=9559561; DOI=10.1093/oxfordjournals.pcp.a029355;
RA   Fujita Y., Takagi H., Hase T.;
RT   "Cloning of the gene encoding a protochlorophyllide reductase: the
RT   physiological significance of the co-existence of light-dependent and
RT   -independent protochlorophyllide reduction systems in the cyanobacterium
RT   Plectonema boryanum.";
RL   Plant Cell Physiol. 39:177-185(1998).
RN   [2]
RP   SEQUENCE REVISION TO 94.
RA   Fujita Y., Yamamoto H.;
RL   Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Phototransformation of protochlorophyllide (Pchlide) to
CC       chlorophyllide (Chlide).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=chlorophyllide a + NADP(+) = H(+) + NADPH +
CC         protochlorophyllide a; Xref=Rhea:RHEA:11132, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:83348,
CC         ChEBI:CHEBI:83350; EC=1.3.1.33;
CC   -!- PATHWAY: Porphyrin-containing compound metabolism; chlorophyll
CC       biosynthesis.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. POR subfamily. {ECO:0000305}.
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DR   EMBL; AB005556; BAA25993.2; -; Genomic_DNA.
DR   PIR; T43931; T43931.
DR   AlphaFoldDB; O66148; -.
DR   SMR; O66148; -.
DR   UniPathway; UPA00668; -.
DR   GO; GO:0016630; F:protochlorophyllide reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR005979; Prochl_reduct.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR44419; PTHR44419; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR01289; LPOR; 1.
PE   3: Inferred from homology;
KW   Chlorophyll biosynthesis; NADP; Oxidoreductase; Photosynthesis.
FT   CHAIN           1..322
FT                   /note="Light-dependent protochlorophyllide reductase"
FT                   /id="PRO_0000219916"
SQ   SEQUENCE   322 AA;  35400 MW;  9233078B0F97D508 CRC64;
     MAQDQKPTVV ITGASSGVGL YAAKALVKRG WHVVMACRNL EKADSAAKSL GMSPDSYTLM
     HIDLGSLDSV RKFVTQFRES GKSLDALVCN AAVYMPLLKE PMRSPEGYEL SVATNHFGHF
     LLCNLLLEDL KHSTHNDPRL IILGTVTANS KELGGKIPIP APADLGDLSG LEAGFKAPIA
     MIDGKPFKAG KAYKDSKLCN MITSRELHRR YHDSTGIVFN TLYPGCVADT PLFRNSLPVF
     QKVFPWFQKN ITGGYVSQEL AGERTAQVVA DPEFKQSGVH WSWGNRQKEG RESFVQELSE
     KVTDDAKAKR MWELSEKLVG LA