POT7_ARATH
ID POT7_ARATH Reviewed; 858 AA.
AC Q9FY75; Q9M7K1;
DT 21-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT 21-NOV-2003, sequence version 2.
DT 25-MAY-2022, entry version 130.
DE RecName: Full=Potassium transporter 7;
DE Short=AtHAK7;
DE Short=AtPOT7;
GN Name=POT7; Synonyms=HAK7, KUP7; OrderedLocusNames=At5g09400;
GN ORFNames=T5E8_200;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 170-370.
RC STRAIN=cv. Columbia;
RA Rubio F., Santa-Maria G.E., Rodriguez-Navarro A.;
RT "Cloning of Arabidopsis and barley cDNAs encoding HAK potassium
RT transporters in root and shoot cells.";
RL Physiol. Plantarum 109:34-43(2000).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11500563; DOI=10.1104/pp.126.4.1646;
RA Maeser P., Thomine S., Schroeder J.I., Ward J.M., Hirschi K., Sze H.,
RA Talke I.N., Amtmann A., Maathuis F.J.M., Sanders D., Harper J.F.,
RA Tchieu J., Gribskov M., Persans M.W., Salt D.E., Kim S.A., Guerinot M.L.;
RT "Phylogenetic relationships within cation transporter families of
RT Arabidopsis.";
RL Plant Physiol. 126:1646-1667(2001).
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-719 AND SER-721, AND
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
CC -!- FUNCTION: Probable potassium transporter.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAC05466.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL391712; CAC05466.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED91387.1; -; Genomic_DNA.
DR EMBL; AF129481; AAF36493.1; -; mRNA.
DR RefSeq; NP_568213.2; NM_120977.3.
DR AlphaFoldDB; Q9FY75; -.
DR BioGRID; 16077; 10.
DR IntAct; Q9FY75; 9.
DR STRING; 3702.AT5G09400.1; -.
DR iPTMnet; Q9FY75; -.
DR PaxDb; Q9FY75; -.
DR PRIDE; Q9FY75; -.
DR ProteomicsDB; 249055; -.
DR EnsemblPlants; AT5G09400.1; AT5G09400.1; AT5G09400.
DR GeneID; 830799; -.
DR Gramene; AT5G09400.1; AT5G09400.1; AT5G09400.
DR KEGG; ath:AT5G09400; -.
DR Araport; AT5G09400; -.
DR TAIR; locus:2184722; AT5G09400.
DR eggNOG; ENOG502QPSA; Eukaryota.
DR HOGENOM; CLU_008142_2_0_1; -.
DR InParanoid; Q9FY75; -.
DR OMA; QLGCNLG; -.
DR OrthoDB; 332035at2759; -.
DR PhylomeDB; Q9FY75; -.
DR PRO; PR:Q9FY75; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FY75; baseline and differential.
DR Genevisible; Q9FY75; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR GO; GO:0005774; C:vacuolar membrane; HDA:TAIR.
DR GO; GO:0005773; C:vacuole; HDA:TAIR.
DR GO; GO:0004016; F:adenylate cyclase activity; IDA:TAIR.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006813; P:potassium ion transport; IMP:TAIR.
DR InterPro; IPR003855; K+_transporter.
DR PANTHER; PTHR30540; PTHR30540; 1.
DR Pfam; PF02705; K_trans; 1.
DR TIGRFAMs; TIGR00794; kup; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Ion transport; Membrane; Phosphoprotein; Potassium;
KW Potassium transport; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..858
FT /note="Potassium transporter 7"
FT /id="PRO_0000209083"
FT TOPO_DOM 1..104
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 126..147
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 169..232
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 233..253
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 254..269
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 270..290
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 291..297
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 298..318
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 319..345
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 346..366
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 367..380
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 381..401
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 402..413
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 414..434
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 435..470
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 471..491
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 492..496
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 497..517
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 518
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 519..539
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 540..552
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 553..573
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 574..858
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 1..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 707..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..62
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 719
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19376835"
FT MOD_RES 721
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19376835"
FT CONFLICT 171
FT /note="D -> N (in Ref. 3; AAF36493)"
FT /evidence="ECO:0000305"
FT CONFLICT 370
FT /note="C -> G (in Ref. 3; AAF36493)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 858 AA; 95354 MW; 75581989555052B8 CRC64;
MAEESSMEGS EKEEIDSSGG GFGDMASMDS IESRWVIQDD DDSEIGVDDD NDGFDGTGLE
SDEDEIPEHR LIRTGPRVDS FDVEALEVPG APRNDYEDLT VGRKVLLAFQ TLGVVFGDVG
TSPLYTFSVM FSKSPVQEKE DVIGALSLVL YTLLLVPLIK YVLVVLWAND DGEGGTFALY
SLISRHAKIS LIPNQLRSDT RISSFRLKVP CPELERSLKL KEKLENSLIL KKILLVLVLA
GTSMVIADGV VTPAMSVMSA VGGLKVGVDV VEQDQVVMIS VAFLVILFSL QKYGTSKMGL
VVGPALLIWF CSLAGIGIYN LIKYDSSVYR AFNPVHIYYF FKRNSINAWY ALGGCILCAT
GSEALFADLC YFSVRSVQLT FVCLVLPCLM LGYMGQAAYL MENHADASQA FFSSVPGSAF
WPVLFIANIA ALIASRTMTT ATFSCIKQST ALGCFPRLKI IHTSRKFMGQ IYIPVLNWFL
LAVCLVVVCS ISSIDEIGNA YGMAELGVMM TTTILVTLIM LLIWQINIVI VIAFLVVFLG
VELVFFSSVI ASVGDGSWII LVFAVIMFGI MYIWNYGSKL RYETEVEQKL SMDLMRELGC
NLGTIRAPGI GLLYNELVKG VPAIFGHFLT TLPAIHSMVI FVCIKYVPVP VVPQNERFLF
RRVCTKSYHL FRCIARYGYK DARKETHQAF EQLLIESLEK FIRREAQERS LESDGNDDSD
SEEDFPGSRV VIGPNGSMYS MGVPLLSEYR DLNKPIMEMN TSSDHTNHHP FDTSSDSSVS
EAEQSLEREL SFIHKAKESG VVYLLGHGDI RARKDSWFIK KLVINYFYTF LRKNCRRGIA
NLSVPQSHLM QVGMTYMV
