POT8_ARATH
ID POT8_ARATH Reviewed; 781 AA.
AC Q9M7J9; Q9LEQ2;
DT 21-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT 21-NOV-2003, sequence version 2.
DT 25-MAY-2022, entry version 124.
DE RecName: Full=Potassium transporter 8;
DE Short=AtHAK8;
DE Short=AtPOT8;
GN Name=POT8; Synonyms=HAK8, KUP8; OrderedLocusNames=At5g14880;
GN ORFNames=T9L3_180;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 88-293.
RC STRAIN=cv. Columbia;
RA Rubio F., Santa-Maria G.E., Rodriguez-Navarro A.;
RT "Cloning of Arabidopsis and barley cDNAs encoding HAK potassium
RT transporters in root and shoot cells.";
RL Physiol. Plantarum 109:34-43(2000).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11500563; DOI=10.1104/pp.126.4.1646;
RA Maeser P., Thomine S., Schroeder J.I., Ward J.M., Hirschi K., Sze H.,
RA Talke I.N., Amtmann A., Maathuis F.J.M., Sanders D., Harper J.F.,
RA Tchieu J., Gribskov M., Persans M.W., Salt D.E., Kim S.A., Guerinot M.L.;
RT "Phylogenetic relationships within cation transporter families of
RT Arabidopsis.";
RL Plant Physiol. 126:1646-1667(2001).
CC -!- FUNCTION: Probable potassium transporter.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
CC {ECO:0000305}.
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DR EMBL; AL391149; CAC01887.1; -; Genomic_DNA.
DR EMBL; CP002688; AED92085.1; -; Genomic_DNA.
DR EMBL; AF129483; AAF36495.1; -; mRNA.
DR PIR; T51433; T51433.
DR RefSeq; NP_196992.1; NM_121492.2.
DR AlphaFoldDB; Q9M7J9; -.
DR STRING; 3702.AT5G14880.1; -.
DR iPTMnet; Q9M7J9; -.
DR PaxDb; Q9M7J9; -.
DR PRIDE; Q9M7J9; -.
DR ProteomicsDB; 249056; -.
DR EnsemblPlants; AT5G14880.1; AT5G14880.1; AT5G14880.
DR GeneID; 831340; -.
DR Gramene; AT5G14880.1; AT5G14880.1; AT5G14880.
DR KEGG; ath:AT5G14880; -.
DR Araport; AT5G14880; -.
DR TAIR; locus:2185515; AT5G14880.
DR eggNOG; ENOG502QPSA; Eukaryota.
DR HOGENOM; CLU_008142_2_0_1; -.
DR InParanoid; Q9M7J9; -.
DR OMA; QHSESND; -.
DR OrthoDB; 332035at2759; -.
DR PhylomeDB; Q9M7J9; -.
DR PRO; PR:Q9M7J9; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9M7J9; baseline and differential.
DR Genevisible; Q9M7J9; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006813; P:potassium ion transport; IBA:GO_Central.
DR InterPro; IPR003855; K+_transporter.
DR PANTHER; PTHR30540; PTHR30540; 1.
DR Pfam; PF02705; K_trans; 1.
DR TIGRFAMs; TIGR00794; kup; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Glycoprotein; Ion transport; Membrane; Potassium;
KW Potassium transport; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..781
FT /note="Potassium transporter 8"
FT /id="PRO_0000209084"
FT TOPO_DOM 1..16
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 38..62
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 63..83
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 84..155
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 156..176
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 177..195
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 217..219
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 220..240
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 241..273
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 274..294
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 295..296
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 297..317
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 318..347
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 348..368
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 369..395
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 396..416
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 417..426
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 427..447
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 448..455
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 456..476
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 477
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 478..498
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 499..781
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 424
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 251
FT /note="Y -> D (in Ref. 3; AAF36495)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 781 AA; 87671 MW; 23E0C39D91A2CE05 CRC64;
MDLERLSPRN PVKKESWWTV LTLAYQSLGV VYGDLATSPL YVYKSTFAED ITHSETNEEI
FGVLSLIFWT LTLIPLVKYV FIVLRADDNG EGGTFALYSL LCRHARISSL PNFQLADEDL
SEYKKNSGEN PMRLKVPGWS LKNTLEKHKF LQNMLLVLAL IGTCMVIGDG VLTPAISVFS
AVSGLELSMS KQQHQYVEVP VVCAILILLF SLQHYGTHRL GFVFAPIVLA WLLCISTIGV
YNIFHWNPHV YKALSPYYIY KFLKKTRKRG WMSLGGILLC ITGSEAMFAD LGHFTQLSIQ
IAFTFAVYPS LILAYMGQAA YLSKHHVLQS DYRIGFYVSV PEQIRWPVLA IAILAAVVGS
QAIITGTFSI IKQCTSLGCF PKVKIVHTSS RMHGQIYIPE INWTLMLLCL AVTVGFRDTK
HISNASGLAV ITVMLVTTCL MSLVIVLCWR KSSLYALAFI FFFGTIEVLY FSASLIKFLE
GAWVPVALSF IFLLIMYVWH YGTLKRYEFD VQNKVSINWL LTLFGSSNLG IVRVHGIGVI
NTELVSGIPA IFSHFITNLP AFHQVVVFLC VKSVPVPHVK PEERFLVGRV GPKEYRLYRC
IARYGYRDVH KDDVEFENDL ICSIAEFIRS DKPLNYSPDP ENESGINERL TVVAASSSNL
EGVQIYEDDG SDKQEPSSSS EVIMVAPSPR FKKRVRFVLP ESARIDRSAE EELTELTEAR
EAGMAFIMGH SYVRAKSGSS VMKKIAINFG YDFLRRNSRG PCYGLSTPHA STLEVGMVYI
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