ID   POTA_MYCPN              Reviewed;         560 AA.
AC   P75059;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 130.
DE   RecName: Full=Spermidine/putrescine import ATP-binding protein PotA {ECO:0000255|HAMAP-Rule:MF_01726};
DE            EC=7.6.2.11 {ECO:0000255|HAMAP-Rule:MF_01726};
GN   Name=potA {ECO:0000255|HAMAP-Rule:MF_01726}; OrderedLocusNames=MPN_055;
GN   ORFNames=MP099;
OS   Mycoplasma pneumoniae (strain ATCC 29342 / M129) (Mycoplasmoides
OS   pneumoniae).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=272634;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29342 / M129;
RX   PubMed=8948633; DOI=10.1093/nar/24.22.4420;
RA   Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.;
RT   "Complete sequence analysis of the genome of the bacterium Mycoplasma
RT   pneumoniae.";
RL   Nucleic Acids Res. 24:4420-4449(1996).
CC   -!- FUNCTION: Part of the ABC transporter complex PotABCD involved in
CC       spermidine/putrescine import. Responsible for energy coupling to the
CC       transport system. {ECO:0000255|HAMAP-Rule:MF_01726}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + polyamine-[polyamine-binding protein]Side 1 = ADP
CC         + phosphate + polyamineSide 2 + [polyamine-binding protein]Side 1.;
CC         EC=7.6.2.11; Evidence={ECO:0000255|HAMAP-Rule:MF_01726};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (PotA),
CC       two transmembrane proteins (PotB and PotC) and a solute-binding protein
CC       (PotD). {ECO:0000255|HAMAP-Rule:MF_01726}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01726};
CC       Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01726}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily.
CC       Spermidine/putrescine importer (TC 3.A.1.11.1) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01726}.
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DR   EMBL; U00089; AAB95747.1; -; Genomic_DNA.
DR   PIR; S73425; S73425.
DR   RefSeq; NP_109743.1; NC_000912.1.
DR   RefSeq; WP_010874412.1; NC_000912.1.
DR   AlphaFoldDB; P75059; -.
DR   STRING; 272634.MPN_055; -.
DR   EnsemblBacteria; AAB95747; AAB95747; MPN_055.
DR   GeneID; 66609304; -.
DR   KEGG; mpn:MPN_055; -.
DR   PATRIC; fig|272634.6.peg.55; -.
DR   HOGENOM; CLU_000604_1_1_14; -.
DR   OMA; IRQKMQV; -.
DR   BioCyc; MPNE272634:G1GJ3-88-MON; -.
DR   Proteomes; UP000000808; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015417; F:ABC-type polyamine transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR008995; Mo/tungstate-bd_C_term_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF50331; SSF50331; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51305; POTA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW   Reference proteome; Translocase; Transport.
FT   CHAIN           1..560
FT                   /note="Spermidine/putrescine import ATP-binding protein
FT                   PotA"
FT                   /id="PRO_0000092751"
FT   DOMAIN          7..449
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01726"
FT   REGION          108..318
FT                   /note="Insert"
FT   BINDING         40..47
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01726"
SQ   SEQUENCE   560 AA;  65131 MW;  8993CAE61A28723D CRC64;
     MNERFLIEIE GLNKTFDDGF VSVRDINLKI KKGEFITILG PSGCGKTTTL RLLAGFEDPT
     YGKIKVNGLD IKDLPIHKRP FATVFQDYAL FSHLTVYKNI AYGLKAMYTK LDPIDKLVEQ
     YHQSLLDKQH RLHKRIERLE KSNANPQLLE QLKQTVVVQQ KQFKQQTETF KQKENARRDA
     IQQRLVQLTK EWESLSKQKL QQLEAEKKLL DKKFEQTERK YQKDAWMATH SEMRLKQFKQ
     EVLALKQLIK TKFKQNEPVD KLQLKLQTLK QKYAAKRQID KEYDKLVLAY NKKDYWTSYW
     ETYSLQQQEA FEKRYLSRKL TKQEQHQKVC AVIELVGLKG NEDKLPEELS GGMKQRVALA
     RSLVIEPDIL LLDEPLSALD AKVRKNLQKE LQKIHQQSGL TFILVTHDQE EALVLSNRIV
     VMNEGNILQV GSPADIYDSP KTEWIANFIG QANIFKGTYL GDLKIKLHSG EVIKTDVDNN
     YVVGKEYKIL IRPEDFDIVP KNKGFFNVRV IDKTYKGLLW KITTKLVDDT IVDLESVNDI
     EVDKTFGVTF DPIDVHLMEV