POTB_MYCGE
ID POTB_MYCGE Reviewed; 285 AA.
AC P47289;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Spermidine/putrescine transport system permease protein PotB homolog;
GN Name=potB; OrderedLocusNames=MG043;
OS Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS (Mycoplasmoides genitalium).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=243273;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT "The minimal gene complement of Mycoplasma genitalium.";
RL Science 270:397-403(1995).
CC -!- FUNCTION: Required for the activity of the bacterial transport system
CC of putrescine and spermidine. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. CysTW subfamily. {ECO:0000305}.
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DR EMBL; L43967; AAC71259.1; -; Genomic_DNA.
DR PIR; G64204; G64204.
DR RefSeq; WP_010869304.1; NC_000908.2.
DR AlphaFoldDB; P47289; -.
DR SMR; P47289; -.
DR STRING; 243273.MG_043; -.
DR EnsemblBacteria; AAC71259; AAC71259; MG_043.
DR KEGG; mge:MG_043; -.
DR eggNOG; COG1176; Bacteria.
DR HOGENOM; CLU_016047_18_8_14; -.
DR OMA; YPIAYGM; -.
DR OrthoDB; 1488093at2; -.
DR BioCyc; MGEN243273:G1GJ2-43-MON; -.
DR Proteomes; UP000000807; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..285
FT /note="Spermidine/putrescine transport system permease
FT protein PotB homolog"
FT /id="PRO_0000060179"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 136..156
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 247..267
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 58..268
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 285 AA; 32101 MW; DED3041909865D6B CRC64;
MHIKKKYWLL LPFFLLMTIF FIIPMAWIIV SGLQSEDGAS ISQKYEPLVS GLGFFNSFWT
SLWISIVTVI VALLFSFPFC YFLSQSKNKI FKAFVISIAT VPIWSSFLIK LIGLKTLLDL
LIGLSLNRVG DNNLTFGSGY TLLGTIYLFT PFMFLPLYNH FCVLPKNLLL ASQDLGYNWI
YSFVKVVIPF SKTAMLSGIA LTFFPALTSV AIAQFLDNSN QAETLGNYIF TLGNNGYDSA
IERGRAAGAI IIAALITFAI YFTVVFLPKI VRIVHNKWKQ HEKAF
