POTB_MYCPN
ID POTB_MYCPN Reviewed; 286 AA.
AC P75058;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Spermidine/putrescine transport system permease protein PotB homolog;
GN Name=potB; OrderedLocusNames=MPN_056; ORFNames=MP098;
OS Mycoplasma pneumoniae (strain ATCC 29342 / M129) (Mycoplasmoides
OS pneumoniae).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=272634;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29342 / M129;
RX PubMed=8948633; DOI=10.1093/nar/24.22.4420;
RA Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.;
RT "Complete sequence analysis of the genome of the bacterium Mycoplasma
RT pneumoniae.";
RL Nucleic Acids Res. 24:4420-4449(1996).
CC -!- FUNCTION: Required for the activity of the bacterial transport system
CC of putrescine and spermidine. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. CysTW subfamily. {ECO:0000305}.
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DR EMBL; U00089; AAB95746.1; -; Genomic_DNA.
DR PIR; S73424; S73424.
DR RefSeq; NP_109744.1; NC_000912.1.
DR RefSeq; WP_010874413.1; NC_000912.1.
DR AlphaFoldDB; P75058; -.
DR SMR; P75058; -.
DR STRING; 272634.MPN_056; -.
DR EnsemblBacteria; AAB95746; AAB95746; MPN_056.
DR KEGG; mpn:MPN_056; -.
DR PATRIC; fig|272634.6.peg.56; -.
DR HOGENOM; CLU_016047_18_8_14; -.
DR OMA; YPIAYGM; -.
DR BioCyc; MPNE272634:G1GJ3-90-MON; -.
DR Proteomes; UP000000808; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..286
FT /note="Spermidine/putrescine transport system permease
FT protein PotB homolog"
FT /id="PRO_0000060180"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 136..156
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 193..213
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 248..268
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 58..264
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 286 AA; 31936 MW; 04313B3A07384CDB CRC64;
MKLSKKYLLA VPFFVLMVIF FVVPMAWIIV SGLQNENGAS ITEKYQPLVG GYSFFQSFWT
SLWTATVTVL VALLVAFPFC YFLSQSKNKV FRSFVIALAT APIWSSFLIK LIGLKTLLDL
VLGLALNRVG DNNLTFGSGY TLIGMIYLFT PFMFLPLYNN FCILPKNLIL ASQDLGYNWI
TSFIKVVIPF SKTAILSGIA LTFFPSLTSV AIAQFLDNSN QNNTLGNYVF TLGNNGYDSA
IERGRASGAI IIAALITFAF YFVVIFAPRI VRLIQTKCLK YRRVNV
