POTB_SALTS
ID POTB_SALTS Reviewed; 287 AA.
AC E1WF94; P0A2J7; Q56060;
DT 08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT 30-NOV-2010, sequence version 1.
DT 03-AUG-2022, entry version 48.
DE RecName: Full=Spermidine/putrescine transport system permease protein PotB;
GN Name=potB; OrderedLocusNames=SL1344_1162;
OS Salmonella typhimurium (strain SL1344).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=216597;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SL1344;
RX PubMed=22538806; DOI=10.1073/pnas.1201061109;
RA Kroger C., Dillon S.C., Cameron A.D., Papenfort K., Sivasankaran S.K.,
RA Hokamp K., Chao Y., Sittka A., Hebrard M., Handler K., Colgan A.,
RA Leekitcharoenphon P., Langridge G.C., Lohan A.J., Loftus B., Lucchini S.,
RA Ussery D.W., Dorman C.J., Thomson N.R., Vogel J., Hinton J.C.;
RT "The transcriptional landscape and small RNAs of Salmonella enterica
RT serovar Typhimurium.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:E1277-E1286(2012).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 276-287.
RC STRAIN=SL1344;
RX PubMed=8861213; DOI=10.1111/j.1365-2958.1996.tb02497.x;
RA Stein M.A., Leung K.Y., Zwick M., Garcia-Del Portillo F., Finlay B.B.;
RT "Identification of a Salmonella virulence gene required for formation of
RT filamentous structures containing lysosomal membrane glycoproteins within
RT epithelial cells.";
RL Mol. Microbiol. 20:151-164(1996).
CC -!- FUNCTION: Required for the activity of the bacterial periplasmic
CC transport system of putrescine and spermidine.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. CysTW subfamily. {ECO:0000305}.
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DR EMBL; FQ312003; CBW17258.1; -; Genomic_DNA.
DR EMBL; U51867; AAA97466.1; -; Genomic_DNA.
DR PIR; S71034; S71034.
DR RefSeq; WP_000799391.1; NZ_QASL01000001.1.
DR AlphaFoldDB; E1WF94; -.
DR SMR; E1WF94; -.
DR EnsemblBacteria; CBW17258; CBW17258; SL1344_1162.
DR KEGG; sey:SL1344_1162; -.
DR PATRIC; fig|216597.6.peg.1290; -.
DR HOGENOM; CLU_016047_18_3_6; -.
DR OMA; RIYAWMI; -.
DR BioCyc; SENT216597:SL1344_RS06045-MON; -.
DR Proteomes; UP000008962; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..287
FT /note="Spermidine/putrescine transport system permease
FT protein PotB"
FT /id="PRO_0000406085"
FT TOPO_DOM 1..10
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 32..70
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 92..99
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 121..145
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 167..197
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 198..218
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 219..251
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 252..272
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 273..287
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 65..271
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 287 AA; 32364 MW; 1A88E932C1F75C1E CRC64;
MKNTSKFQNV VIVTIVGWLV LFVFLPNLMI IGTSFLTRDD ASFVKMVFTL DNYARLLDPL
YFEVLLHSLN MALIATLSCL VLGYPFAWFL AKLPEKIRPL LLFLLIVPFW TNSLIRIYGL
KIFLSTKGYL NEFLLWLGVI DTPIRIMFTP SAVIIGLVYI LLPFMVMPLY SSIEKLDKPL
LEAARDLGAS KMQTFIRIII PLTMPGIVAG CLLVMLPAMG LFYVSDLMGG AKNLLIGNVI
KVQFLNIRDW PFGAATSITL TIVMGLMLLI YWRASRLLNK KVSDISD
