ID   POTC_MYCGE              Reviewed;         284 AA.
AC   P47290;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Spermidine/putrescine transport system permease protein PotC homolog;
GN   Name=potC; OrderedLocusNames=MG044;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
CC   -!- FUNCTION: Required for the activity of the bacterial transport system
CC       of putrescine and spermidine. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. CysTW subfamily. {ECO:0000305}.
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DR   EMBL; L43967; AAC71260.1; -; Genomic_DNA.
DR   PIR; H64204; H64204.
DR   RefSeq; WP_009885706.1; NZ_AAGX01000003.1.
DR   AlphaFoldDB; P47290; -.
DR   SMR; P47290; -.
DR   STRING; 243273.MG_044; -.
DR   EnsemblBacteria; AAC71260; AAC71260; MG_044.
DR   KEGG; mge:MG_044; -.
DR   eggNOG; COG1177; Bacteria.
DR   HOGENOM; CLU_016047_3_0_14; -.
DR   OMA; FPMFVWG; -.
DR   OrthoDB; 1264541at2; -.
DR   BioCyc; MGEN243273:G1GJ2-44-MON; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..284
FT                   /note="Spermidine/putrescine transport system permease
FT                   protein PotC homolog"
FT                   /id="PRO_0000060185"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        116..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        189..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        242..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          72..263
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   284 AA;  31669 MW;  2746C49F2C3AF175 CRC64;
     MKKHFKNLIK NSYFFLLITL IYLPLLIVVL VSLNGSSSRG NIVLDFGNVL NPNPDSKSAY
     LRLGETDFAT PLINSIIIGV ITVLVSVPIA VISAFALLRT RNALKKTIFG ITNFSLATPD
     IITAISLVLL FANTWLSFNQ QLGFFTIITS HISFSVPYAL ILIYPKIQKL NPNLILASQD
     LGYSPLKTFF HITLPYLMPS IFSAVLVVFA TSFDDYVITS LVQGSVKTIA TELYSFRKGI
     KAWAIAFGSI LILISVLGVC LITLQKYLRE KRKEIIKIRQ WKNS