ID   POTD2_HAEIN             Reviewed;         350 AA.
AC   P44731;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   06-JUN-2002, sequence version 2.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Spermidine/putrescine-binding periplasmic protein 2;
DE            Short=SPBP;
DE   Flags: Precursor;
GN   Name=potD-A; OrderedLocusNames=HI_0498;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Required for the activity of the bacterial periplasmic
CC       transport system of putrescine and spermidine. Polyamine binding
CC       protein (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein PotD/PotF
CC       family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAC22155.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; L42023; AAC22155.1; ALT_INIT; Genomic_DNA.
DR   PIR; E64072; E64072.
DR   RefSeq; NP_438656.2; NC_000907.1.
DR   RefSeq; WP_005666442.1; NC_000907.1.
DR   AlphaFoldDB; P44731; -.
DR   SMR; P44731; -.
DR   STRING; 71421.HI_0498; -.
DR   EnsemblBacteria; AAC22155; AAC22155; HI_0498.
DR   KEGG; hin:HI_0498; -.
DR   PATRIC; fig|71421.8.peg.516; -.
DR   eggNOG; COG0687; Bacteria.
DR   HOGENOM; CLU_026974_1_3_6; -.
DR   PhylomeDB; P44731; -.
DR   BioCyc; HINF71421:G1GJ1-511-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0019808; F:polyamine binding; IEA:InterPro.
DR   GO; GO:0015846; P:polyamine transport; IEA:InterPro.
DR   InterPro; IPR006059; SBP.
DR   InterPro; IPR001188; Sperm_putr-bd.
DR   Pfam; PF13416; SBP_bac_8; 1.
DR   PIRSF; PIRSF019574; Periplasmic_polyamine_BP; 1.
DR   PRINTS; PR00909; SPERMDNBNDNG.
PE   3: Inferred from homology;
KW   Periplasm; Reference proteome; Signal; Transport.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..350
FT                   /note="Spermidine/putrescine-binding periplasmic protein 2"
FT                   /id="PRO_0000031841"
SQ   SEQUENCE   350 AA;  39647 MW;  D764F90754618A47 CRC64;
     MKKFFAHSLK NLFLSTTALF AASAFANNKL YVYNWTDYVP SDLVAQFSKE TGIEVIYSTF
     ESNEEMYAKL KLTQNTGSGY DLVFPSSYYV NKMIKEKMLQ PIDQSKLTNI HQIPKHLLNK
     EFDPENKYSL PYVYGLTGIE VNADEIDPKT ITSWADLWKP EFKGKVLMTS DAREVFHVAL
     LLDGKSPNTT NEEDIKTAYE RLEKLLPNVA TFNSDSPEVP YVQGEVAIGM IWNGSAYLAQ
     KENQSLQFVY PKEGAIFWMD NYAIPTTAKN VEGAHKFIDF LLRPENAKIV IERMGFSMPN
     NGAKTLLSAE VANDPKLFPP AEEVEKGIMQ GDVGEAVDIY EKYWGKLKTN