ID   POTD_SALTI              Reviewed;         348 AA.
AC   P0A2C8; P97012;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Spermidine/putrescine-binding periplasmic protein;
DE            Short=SPBP;
DE   Flags: Precursor;
GN   Name=potD; OrderedLocusNames=STY1262, t1698;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Required for the activity of the bacterial periplasmic
CC       transport system of putrescine and spermidine. Polyamine binding
CC       protein (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein PotD/PotF
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL513382; CAD08346.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO69323.1; -; Genomic_DNA.
DR   RefSeq; NP_455714.1; NC_003198.1.
DR   RefSeq; WP_000759329.1; NZ_WSUR01000030.1.
DR   AlphaFoldDB; P0A2C8; -.
DR   SMR; P0A2C8; -.
DR   STRING; 220341.16502391; -.
DR   EnsemblBacteria; AAO69323; AAO69323; t1698.
DR   KEGG; stt:t1698; -.
DR   KEGG; sty:STY1262; -.
DR   PATRIC; fig|220341.7.peg.1266; -.
DR   eggNOG; COG0687; Bacteria.
DR   HOGENOM; CLU_026974_1_3_6; -.
DR   OMA; FWMDNYA; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0019808; F:polyamine binding; IEA:InterPro.
DR   GO; GO:0015846; P:polyamine transport; IEA:InterPro.
DR   InterPro; IPR006059; SBP.
DR   InterPro; IPR001188; Sperm_putr-bd.
DR   Pfam; PF13416; SBP_bac_8; 1.
DR   PIRSF; PIRSF019574; Periplasmic_polyamine_BP; 1.
DR   PRINTS; PR00909; SPERMDNBNDNG.
PE   3: Inferred from homology;
KW   Periplasm; Signal; Transport.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000250"
FT   CHAIN           24..348
FT                   /note="Spermidine/putrescine-binding periplasmic protein"
FT                   /id="PRO_0000031838"
SQ   SEQUENCE   348 AA;  39021 MW;  48AD0FDE2AC075A3 CRC64;
     MKKWSRHLLA AGALALGMSA AHASDNDTLY FYNWTEYVPP GLLEQFTKET GIKVIYSTYE
     SNETMYAKLK TYKDGAYDLV VPSTYYVDKM RKEGMIQKID KSKLTNFHNL DPEMLNKPFD
     PNNDYSVPYI WGATAIGVNS DAIDPKTITS WADLWKPEYK NSLLLTDDAR EVFQMALRKL
     GYSGNTTDPK EIEAAYEELK KLMPNVAAFN SDNPANPYME GEVNLGMVWN GSAFVARQAG
     TPLEVVWPKE GGIFWMDSLA IPANAKNKEG ALKLINFLLR PDVAKEVAET IGYPTPNLAA
     RKLLSPEVAN DKSLYPDAQT ISKGEWQNDV GDASAIYEEY YQKLKAGR