POTD_SHIFL
ID POTD_SHIFL Reviewed; 348 AA.
AC P0AFL0; P23861;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 25-MAY-2022, entry version 93.
DE RecName: Full=Spermidine/putrescine-binding periplasmic protein;
DE Short=SPBP;
DE Flags: Precursor;
GN Name=potD; OrderedLocusNames=SF1125, S1205;
OS Shigella flexneri.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- FUNCTION: Required for the activity of the bacterial periplasmic
CC transport system of putrescine and spermidine. Polyamine binding
CC protein (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the bacterial solute-binding protein PotD/PotF
CC family. {ECO:0000305}.
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DR EMBL; AE005674; AAN42743.1; -; Genomic_DNA.
DR EMBL; AE014073; AAP16632.1; -; Genomic_DNA.
DR RefSeq; NP_707036.1; NC_004337.2.
DR RefSeq; WP_000759317.1; NZ_WPGW01000001.1.
DR AlphaFoldDB; P0AFL0; -.
DR SMR; P0AFL0; -.
DR STRING; 198214.SF1125; -.
DR EnsemblBacteria; AAN42743; AAN42743; SF1125.
DR EnsemblBacteria; AAP16632; AAP16632; S1205.
DR GeneID; 1024061; -.
DR GeneID; 66670610; -.
DR KEGG; sfl:SF1125; -.
DR KEGG; sfx:S1205; -.
DR PATRIC; fig|198214.7.peg.1316; -.
DR HOGENOM; CLU_026974_1_3_6; -.
DR OMA; FWMDNYA; -.
DR OrthoDB; 1264541at2; -.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0019808; F:polyamine binding; IEA:InterPro.
DR GO; GO:0015846; P:polyamine transport; IEA:InterPro.
DR InterPro; IPR006059; SBP.
DR InterPro; IPR001188; Sperm_putr-bd.
DR Pfam; PF13416; SBP_bac_8; 1.
DR PIRSF; PIRSF019574; Periplasmic_polyamine_BP; 1.
DR PRINTS; PR00909; SPERMDNBNDNG.
PE 3: Inferred from homology;
KW Periplasm; Reference proteome; Signal; Transport.
FT SIGNAL 1..23
FT /evidence="ECO:0000250"
FT CHAIN 24..348
FT /note="Spermidine/putrescine-binding periplasmic protein"
FT /id="PRO_0000045118"
SQ SEQUENCE 348 AA; 38867 MW; 1E6EB7A6B4EC63AB CRC64;
MKKWSRHLLA AGALALGMSA AHADDNNTLY FYNWTEYVPP GLLEQFTKET GIKVIYSTYE
SNETMYAKLK TYKDGAYDLV VPSTYYVDKM RKEGMIQKID KSKLTNFSNL DPDMLNKPFD
PNNDYSIPYI WGATAIGVNG DAVDPKSVTS WADLWKPEYK GSLLLTDDAR EVFQMALRKL
GYSGNTTDPK EIEAAYNELK KLMPNVAAFN SDNPANPYME GEVNLGMIWN GSAFVARQAG
TPIDVVWPKE GGIFWMDSLA IPANAKNKEG ALKLINFLLR PDVAKQVAET IGYPTPNLAA
RKLLSPEVAN DKTLYPDAET IKNGEWQNDV GAASSIYEEY YQKLKAGR
