ID   POX18_CANMA             Reviewed;         127 AA.
AC   Q00680;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Oleate-induced peroxisomal protein POX18;
DE            Short=PXP-18;
DE   AltName: Full=Lipid-transfer protein;
GN   Name=POX18;
OS   Candida maltosa (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=5479;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 28140 / CBS 5611 / IAM 12247 / JCM 1504 / NBRC 1977;
RX   PubMed=1937042; DOI=10.1016/0378-1119(91)90566-t;
RA   Hwang C.W., Yano K., Takagi M.;
RT   "Sequences of two tandem genes regulated by carbon sources, one being
RT   essential for n-alkane assimilation in Candida maltosa.";
RL   Gene 106:61-69(1991).
CC   -!- FUNCTION: Is involved in beta-oxidation of long-chain fatty acids. Its
CC       exact function is unknown, but possesses a nonspecific lipid-transfer
CC       activity, despite the absence of a cysteine residue thought to be
CC       essential for the activity of its mammalian counterparts.
CC   -!- PATHWAY: Lipid metabolism; fatty acid metabolism.
CC   -!- SUBUNIT: Monomer.
CC   -!- SUBCELLULAR LOCATION: Peroxisome.
CC   -!- INDUCTION: By alkanes or fatty acids; repressed by glucose.
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DR   EMBL; M61102; AAA34359.1; -; Genomic_DNA.
DR   PIR; JT0590; JT0590.
DR   AlphaFoldDB; Q00680; -.
DR   SMR; Q00680; -.
DR   OMA; TASWHID; -.
DR   UniPathway; UPA00199; -.
DR   GO; GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.30.1050.10; -; 1.
DR   InterPro; IPR039543; POX18/UbiT/NSL-TP1.
DR   InterPro; IPR003033; SCP2_sterol-bd_dom.
DR   InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR   PANTHER; PTHR10094; PTHR10094; 1.
DR   Pfam; PF02036; SCP2; 1.
DR   SUPFAM; SSF55718; SSF55718; 1.
PE   2: Evidence at transcript level;
KW   Lipid-binding; Peroxisome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..127
FT                   /note="Oleate-induced peroxisomal protein POX18"
FT                   /id="PRO_0000058527"
FT   DOMAIN          14..119
FT                   /note="SCP2"
FT                   /evidence="ECO:0000255"
FT   REGION          33..41
FT                   /note="Hydrophobic"
FT   REGION          43..52
FT                   /note="Hydrophilic"
SQ   SEQUENCE   127 AA;  13818 MW;  5EAD82D33118C30E CRC64;
     MSVEVDGFNA SPLFKELHEG LADKSKAEEA VKAVNAVIVI TLKNKEGKEQ SWVLDLKKAG
     TLAKVDGAAP KGDVQLILKD VDFVKLANNK VNGQKLFMNG KLKVKGNMMK ATAIESVFKK
     LDPRPKL