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PP121_ARATH
ID   PP121_ARATH             Reviewed;         895 AA.
AC   Q9CA56;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Pentatricopeptide repeat-containing protein At1g74600, chloroplastic;
DE   Flags: Precursor;
GN   Name=PCMP-E69; OrderedLocusNames=At1g74600; ORFNames=F1M20.28;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY.
RX   PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA   Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA   Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA   Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA   Taconnat L., Small I.;
RT   "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT   reveals their essential role in organelle biogenesis.";
RL   Plant Cell 16:2089-2103(2004).
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the PPR family. PCMP-E subfamily. {ECO:0000305}.
CC   -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC       URL="https://ppr.plantenergy.uwa.edu.au";
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DR   EMBL; AC011765; AAG52351.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE35614.1; -; Genomic_DNA.
DR   PIR; B96775; B96775.
DR   RefSeq; NP_177599.1; NM_106119.2.
DR   AlphaFoldDB; Q9CA56; -.
DR   SMR; Q9CA56; -.
DR   STRING; 3702.AT1G74600.1; -.
DR   iPTMnet; Q9CA56; -.
DR   PaxDb; Q9CA56; -.
DR   PRIDE; Q9CA56; -.
DR   ProteomicsDB; 249402; -.
DR   EnsemblPlants; AT1G74600.1; AT1G74600.1; AT1G74600.
DR   GeneID; 843800; -.
DR   Gramene; AT1G74600.1; AT1G74600.1; AT1G74600.
DR   KEGG; ath:AT1G74600; -.
DR   Araport; AT1G74600; -.
DR   TAIR; locus:2019130; AT1G74600.
DR   eggNOG; KOG4197; Eukaryota.
DR   HOGENOM; CLU_002706_15_6_1; -.
DR   InParanoid; Q9CA56; -.
DR   OMA; RSIWSAF; -.
DR   OrthoDB; 1344243at2759; -.
DR   PhylomeDB; Q9CA56; -.
DR   PRO; PR:Q9CA56; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9CA56; baseline and differential.
DR   Genevisible; Q9CA56; AT.
DR   GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR   GO; GO:0005739; C:mitochondrion; IDA:TAIR.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0080156; P:mitochondrial mRNA modification; IMP:TAIR.
DR   GO; GO:0009451; P:RNA modification; IBA:GO_Central.
DR   Gene3D; 1.25.40.10; -; 7.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF01535; PPR; 7.
DR   Pfam; PF13041; PPR_2; 4.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   TIGRFAMs; TIGR00756; PPR; 8.
DR   PROSITE; PS51375; PPR; 19.
PE   3: Inferred from homology;
KW   Chloroplast; Plastid; Reference proteome; Repeat; Transit peptide.
FT   TRANSIT         1..71
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           72..895
FT                   /note="Pentatricopeptide repeat-containing protein
FT                   At1g74600, chloroplastic"
FT                   /id="PRO_0000342862"
FT   REPEAT          83..113
FT                   /note="PPR 1"
FT   REPEAT          114..148
FT                   /note="PPR 2"
FT   REPEAT          149..183
FT                   /note="PPR 3"
FT   REPEAT          184..214
FT                   /note="PPR 4"
FT   REPEAT          215..249
FT                   /note="PPR 5"
FT   REPEAT          250..280
FT                   /note="PPR 6"
FT   REPEAT          284..314
FT                   /note="PPR 7"
FT   REPEAT          315..349
FT                   /note="PPR 8"
FT   REPEAT          350..384
FT                   /note="PPR 9"
FT   REPEAT          385..415
FT                   /note="PPR 10"
FT   REPEAT          417..451
FT                   /note="PPR 11"
FT   REPEAT          452..483
FT                   /note="PPR 12"
FT   REPEAT          484..514
FT                   /note="PPR 13"
FT   REPEAT          515..549
FT                   /note="PPR 14"
FT   REPEAT          550..584
FT                   /note="PPR 15"
FT   REPEAT          585..615
FT                   /note="PPR 16"
FT   REPEAT          616..650
FT                   /note="PPR 17"
FT   REPEAT          651..685
FT                   /note="PPR 18"
FT   REPEAT          686..716
FT                   /note="PPR 19"
FT   REPEAT          717..751
FT                   /note="PPR 20"
FT   REPEAT          752..787
FT                   /note="PPR 21"
FT   REPEAT          788..818
FT                   /note="PPR 22"
FT   REGION          824..895
FT                   /note="Type E motif; degenerate"
SQ   SEQUENCE   895 AA;  98652 MW;  1F15157CDBBBEFA8 CRC64;
     MNCLANESLN SLKISPFSTS RLLSSVTNFR NQLSFSSKDS SSSSAPFNPF RFFNDQSNSR
     LCNLRTTKIL QAHLLRRYLL PFDVFLTKSL LSWYSNSGSM ADAAKLFDTI PQPDVVSCNI
     MISGYKQHRL FEESLRFFSK MHFLGFEANE ISYGSVISAC SALQAPLFSE LVCCHTIKMG
     YFFYEVVESA LIDVFSKNLR FEDAYKVFRD SLSANVYCWN TIIAGALRNQ NYGAVFDLFH
     EMCVGFQKPD SYTYSSVLAA CASLEKLRFG KVVQARVIKC GAEDVFVCTA IVDLYAKCGH
     MAEAMEVFSR IPNPSVVSWT VMLSGYTKSN DAFSALEIFK EMRHSGVEIN NCTVTSVISA
     CGRPSMVCEA SQVHAWVFKS GFYLDSSVAA ALISMYSKSG DIDLSEQVFE DLDDIQRQNI
     VNVMITSFSQ SKKPGKAIRL FTRMLQEGLR TDEFSVCSLL SVLDCLNLGK QVHGYTLKSG
     LVLDLTVGSS LFTLYSKCGS LEESYKLFQG IPFKDNACWA SMISGFNEYG YLREAIGLFS
     EMLDDGTSPD ESTLAAVLTV CSSHPSLPRG KEIHGYTLRA GIDKGMDLGS ALVNMYSKCG
     SLKLARQVYD RLPELDPVSC SSLISGYSQH GLIQDGFLLF RDMVMSGFTM DSFAISSILK
     AAALSDESSL GAQVHAYITK IGLCTEPSVG SSLLTMYSKF GSIDDCCKAF SQINGPDLIA
     WTALIASYAQ HGKANEALQV YNLMKEKGFK PDKVTFVGVL SACSHGGLVE ESYFHLNSMV
     KDYGIEPENR HYVCMVDALG RSGRLREAES FINNMHIKPD ALVWGTLLAA CKIHGEVELG
     KVAAKKAIEL EPSDAGAYIS LSNILAEVGE WDEVEETRKL MKGTGVQKEP GWSSV
 
 
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