PP127_ARATH
ID PP127_ARATH Reviewed; 695 AA.
AC O49287;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 25-MAY-2022, entry version 116.
DE RecName: Full=Putative pentatricopeptide repeat-containing protein At1g77010, mitochondrial;
DE Flags: Precursor;
GN Name=PCMP-E5; OrderedLocusNames=At1g77010; ORFNames=F22K20.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=10809006; DOI=10.1023/a:1006352315928;
RA Aubourg S., Boudet N., Kreis M., Lecharny A.;
RT "In Arabidopsis thaliana, 1% of the genome codes for a novel protein family
RT unique to plants.";
RL Plant Mol. Biol. 42:603-613(2000).
RN [4]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the PPR family. PCMP-E subfamily. {ECO:0000305}.
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AC002291; AAC00623.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35925.1; -; Genomic_DNA.
DR PIR; B96799; B96799.
DR RefSeq; NP_177827.1; NM_106352.2.
DR AlphaFoldDB; O49287; -.
DR SMR; O49287; -.
DR iPTMnet; O49287; -.
DR PaxDb; O49287; -.
DR PRIDE; O49287; -.
DR ProteomicsDB; 249406; -.
DR EnsemblPlants; AT1G77010.1; AT1G77010.1; AT1G77010.
DR GeneID; 844037; -.
DR Gramene; AT1G77010.1; AT1G77010.1; AT1G77010.
DR KEGG; ath:AT1G77010; -.
DR Araport; AT1G77010; -.
DR TAIR; locus:2025242; AT1G77010.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_002706_0_6_1; -.
DR InParanoid; O49287; -.
DR OMA; IGGCKAQ; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; O49287; -.
DR PRO; PR:O49287; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; O49287; baseline and differential.
DR Genevisible; O49287; AT.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0009451; P:RNA modification; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 6.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR045215; PPR_prot_plant.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR24015; PTHR24015; 3.
DR Pfam; PF01535; PPR; 11.
DR Pfam; PF12854; PPR_1; 1.
DR Pfam; PF13041; PPR_2; 1.
DR TIGRFAMs; TIGR00756; PPR; 6.
DR PROSITE; PS51375; PPR; 19.
PE 3: Inferred from homology;
KW Mitochondrion; Reference proteome; Repeat; Transit peptide.
FT TRANSIT 1..64
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 65..695
FT /note="Putative pentatricopeptide repeat-containing protein
FT At1g77010, mitochondrial"
FT /id="PRO_0000342868"
FT REPEAT 61..91
FT /note="PPR 1"
FT REPEAT 92..122
FT /note="PPR 2"
FT REPEAT 123..157
FT /note="PPR 3"
FT REPEAT 159..184
FT /note="PPR 4"
FT REPEAT 186..220
FT /note="PPR 5"
FT REPEAT 221..251
FT /note="PPR 6"
FT REPEAT 252..282
FT /note="PPR 7"
FT REPEAT 283..313
FT /note="PPR 8"
FT REPEAT 317..351
FT /note="PPR 9"
FT REPEAT 352..382
FT /note="PPR 10"
FT REPEAT 383..417
FT /note="PPR 11"
FT REPEAT 418..448
FT /note="PPR 12"
FT REPEAT 449..483
FT /note="PPR 13"
FT REPEAT 484..514
FT /note="PPR 14"
FT REPEAT 515..549
FT /note="PPR 15"
FT REPEAT 550..585
FT /note="PPR 16"
FT REPEAT 586..616
FT /note="PPR 17"
FT REGION 621..695
FT /note="Type E motif; degenerate"
SQ SEQUENCE 695 AA; 77874 MW; 627BD46DBED4969F CRC64;
MILKYNSSYR FYLSSSFLQA MEVDCRRYYV RLLQSCSSRN RETLWRQTNG LLLKKGFLSS
IVIVANHLLQ MYSRSGKMGI ARNLFDEMPD RNYFSWNTMI EGYMNSGEKG TSLRFFDMMP
ERDGYSWNVV VSGFAKAGEL SVARRLFNAM PEKDVVTLNS LLHGYILNGY AEEALRLFKE
LNFSADAITL TTVLKACAEL EALKCGKQIH AQILIGGVEC DSKMNSSLVN VYAKCGDLRM
ASYMLEQIRE PDDHSLSALI SGYANCGRVN ESRGLFDRKS NRCVILWNSM ISGYIANNMK
MEALVLFNEM RNETREDSRT LAAVINACIG LGFLETGKQM HCHACKFGLI DDIVVASTLL
DMYSKCGSPM EACKLFSEVE SYDTILLNSM IKVYFSCGRI DDAKRVFERI ENKSLISWNS
MTNGFSQNGC TVETLEYFHQ MHKLDLPTDE VSLSSVISAC ASISSLELGE QVFARATIVG
LDSDQVVSSS LIDLYCKCGF VEHGRRVFDT MVKSDEVPWN SMISGYATNG QGFEAIDLFK
KMSVAGIRPT QITFMVVLTA CNYCGLVEEG RKLFESMKVD HGFVPDKEHF SCMVDLLARA
GYVEEAINLV EEMPFDVDGS MWSSILRGCV ANGYKAMGKK AAEKIIELEP ENSVAYVQLS
AIFATSGDWE SSALVRKLMR ENNVTKNPGS SWTDC
