PP144_ARATH
ID PP144_ARATH Reviewed; 613 AA.
AC Q1PFA6; A0MEI0; O64507;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 16-DEC-2008, sequence version 2.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=Pentatricopeptide repeat-containing protein At2g02750;
GN Name=PCMP-E22; OrderedLocusNames=At2g02750; ORFNames=T20F6.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [5]
RP GENE FAMILY.
RX PubMed=10809006; DOI=10.1023/a:1006352315928;
RA Aubourg S., Boudet N., Kreis M., Lecharny A.;
RT "In Arabidopsis thaliana, 1% of the genome codes for a novel protein family
RT unique to plants.";
RL Plant Mol. Biol. 42:603-613(2000).
RN [6]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
CC -!- SIMILARITY: Belongs to the PPR family. PCMP-E subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABK28160.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
CC Sequence=BX821054; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AC002521; AAC05347.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC05620.1; -; Genomic_DNA.
DR EMBL; DQ446457; ABE65422.1; -; Genomic_DNA.
DR EMBL; DQ652951; ABK28160.1; ALT_SEQ; Genomic_DNA.
DR EMBL; BX821054; -; NOT_ANNOTATED_CDS; mRNA.
DR PIR; T00853; T00853.
DR RefSeq; NP_178378.1; NM_126330.3.
DR AlphaFoldDB; Q1PFA6; -.
DR SMR; Q1PFA6; -.
DR STRING; 3702.AT2G02750.1; -.
DR PaxDb; Q1PFA6; -.
DR PRIDE; Q1PFA6; -.
DR ProteomicsDB; 250492; -.
DR EnsemblPlants; AT2G02750.1; AT2G02750.1; AT2G02750.
DR GeneID; 814804; -.
DR Gramene; AT2G02750.1; AT2G02750.1; AT2G02750.
DR KEGG; ath:AT2G02750; -.
DR Araport; AT2G02750; -.
DR TAIR; locus:2058812; AT2G02750.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_002706_0_1_1; -.
DR InParanoid; Q1PFA6; -.
DR OMA; IAGMMLN; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; Q1PFA6; -.
DR PRO; PR:Q1PFA6; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q1PFA6; baseline and differential.
DR Genevisible; Q1PFA6; AT.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0009451; P:RNA modification; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 5.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR045215; PPR_prot_plant.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR24015; PTHR24015; 1.
DR Pfam; PF01535; PPR; 3.
DR Pfam; PF12854; PPR_1; 1.
DR Pfam; PF13041; PPR_2; 2.
DR Pfam; PF13812; PPR_3; 1.
DR TIGRFAMs; TIGR00756; PPR; 7.
DR PROSITE; PS51375; PPR; 11.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat.
FT CHAIN 1..613
FT /note="Pentatricopeptide repeat-containing protein
FT At2g02750"
FT /id="PRO_0000356004"
FT REPEAT 30..64
FT /note="PPR 1"
FT REPEAT 65..99
FT /note="PPR 2"
FT REPEAT 101..126
FT /note="PPR 3"
FT REPEAT 128..162
FT /note="PPR 4"
FT REPEAT 163..193
FT /note="PPR 5"
FT REPEAT 194..228
FT /note="PPR 6"
FT REPEAT 230..264
FT /note="PPR 7"
FT REPEAT 265..295
FT /note="PPR 8"
FT REPEAT 297..331
FT /note="PPR 9"
FT REPEAT 332..366
FT /note="PPR 10"
FT REPEAT 367..401
FT /note="PPR 11"
FT REPEAT 402..432
FT /note="PPR 12"
FT REPEAT 435..469
FT /note="PPR 13"
FT REPEAT 470..500
FT /note="PPR 14"
FT REPEAT 506..539
FT /note="PPR 15"
FT REGION 540..613
FT /note="Type E motif; degenerate"
FT CONFLICT 434
FT /note="K -> R (in Ref. 3; ABE65422)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 613 AA; 67936 MW; F42EA6B95C7E4DD2 CRC64;
MINLTRQRYR VSNLVTGGTS LDVILSHSPN KFTFPPLLKS CAKLGDVVQG RILHAQVVKT
GFFVDVFTAT ALVSMYMKVK QVTDALKVLD EMPERGIASV NAAVSGLLEN GFCRDAFRMF
GDARVSGSGM NSVTVASVLG GCGDIEGGMQ LHCLAMKSGF EMEVYVGTSL VSMYSRCGEW
VLAARMFEKV PHKSVVTYNA FISGLMENGV MNLVPSVFNL MRKFSSEEPN DVTFVNAITA
CASLLNLQYG RQLHGLVMKK EFQFETMVGT ALIDMYSKCR CWKSAYIVFT ELKDTRNLIS
WNSVISGMMI NGQHETAVEL FEKLDSEGLK PDSATWNSLI SGFSQLGKVI EAFKFFERML
SVVMVPSLKC LTSLLSACSD IWTLKNGKEI HGHVIKAAAE RDIFVLTSLI DMYMKCGLSS
WARRIFDRFE PKPKDPVFWN VMISGYGKHG ECESAIEIFE LLREEKVEPS LATFTAVLSA
CSHCGNVEKG SQIFRLMQEE YGYKPSTEHI GCMIDLLGRS GRLREAKEVI DQMSEPSSSV
YSSLLGSCRQ HLDPVLGEEA AMKLAELEPE NPAPFVILSS IYAALERWED VESIRQVIDQ
KQLVKLPGLS LSG
