PP145_ARATH
ID PP145_ARATH Reviewed; 603 AA.
AC Q8LK93; O80613;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 16-DEC-2008, sequence version 2.
DT 25-MAY-2022, entry version 108.
DE RecName: Full=Pentatricopeptide repeat-containing protein At2g02980, chloroplastic {ECO:0000305};
DE AltName: Full=Protein ORGANELLE TRANSCRIPT PROCESSING 85 {ECO:0000303|PubMed:19934379};
DE Flags: Precursor;
GN Name=PCMP-H26; Synonyms=OTP85 {ECO:0000303|PubMed:19934379};
GN OrderedLocusNames=At2g02980; ORFNames=T17M13.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=16244158; DOI=10.1104/pp.105.063479;
RA Xiao Y.-L., Smith S.R., Ishmael N., Redman J.C., Kumar N., Monaghan E.L.,
RA Ayele M., Haas B.J., Wu H.C., Town C.D.;
RT "Analysis of the cDNAs of hypothetical genes on Arabidopsis chromosome 2
RT reveals numerous transcript variants.";
RL Plant Physiol. 139:1323-1337(2005).
RN [4]
RP GENE FAMILY.
RX PubMed=10809006; DOI=10.1023/a:1006352315928;
RA Aubourg S., Boudet N., Kreis M., Lecharny A.;
RT "In Arabidopsis thaliana, 1% of the genome codes for a novel protein family
RT unique to plants.";
RL Plant Mol. Biol. 42:603-613(2000).
RN [5]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
RN [6]
RP FUNCTION, SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
RX PubMed=19934379; DOI=10.1105/tpc.109.071472;
RA Hammani K., Okuda K., Tanz S.K., Chateigner-Boutin A.L., Shikanai T.,
RA Small I.;
RT "A study of new Arabidopsis chloroplast RNA editing mutants reveals general
RT features of editing factors and their target sites.";
RL Plant Cell 21:3686-3699(2009).
CC -!- FUNCTION: Involved in RNA editing event in chloroplasts. Required for
CC the editing of a single site in ndhD transcript, which is a plastid-
CC encoded subunits of the chloroplast NAD(P)H dehydrogenase (NDH)
CC complex. Not essential for the activity of the NDH complex of the
CC photosynthetic electron transport chain. {ECO:0000269|PubMed:19934379}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000269|PubMed:19934379}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions. {ECO:0000269|PubMed:19934379}.
CC -!- SIMILARITY: Belongs to the PPR family. PCMP-H subfamily. {ECO:0000305}.
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AC004138; AAC32916.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC05651.1; -; Genomic_DNA.
DR EMBL; AF517844; AAM77644.1; -; mRNA.
DR PIR; H84442; H84442.
DR RefSeq; NP_178398.1; NM_126350.3.
DR AlphaFoldDB; Q8LK93; -.
DR SMR; Q8LK93; -.
DR STRING; 3702.AT2G02980.1; -.
DR PaxDb; Q8LK93; -.
DR PRIDE; Q8LK93; -.
DR ProteomicsDB; 250493; -.
DR EnsemblPlants; AT2G02980.1; AT2G02980.1; AT2G02980.
DR GeneID; 814827; -.
DR Gramene; AT2G02980.1; AT2G02980.1; AT2G02980.
DR KEGG; ath:AT2G02980; -.
DR Araport; AT2G02980; -.
DR TAIR; locus:2056740; AT2G02980.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_002706_37_8_1; -.
DR InParanoid; Q8LK93; -.
DR OMA; MYTECND; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; Q8LK93; -.
DR PRO; PR:Q8LK93; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8LK93; baseline and differential.
DR Genevisible; Q8LK93; AT.
DR GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:1900865; P:chloroplast RNA modification; IBA:GO_Central.
DR GO; GO:0031425; P:chloroplast RNA processing; IMP:TAIR.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; -; 2.
DR InterPro; IPR032867; DYW_dom.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF14432; DYW_deaminase; 1.
DR Pfam; PF01535; PPR; 2.
DR Pfam; PF13041; PPR_2; 3.
DR SUPFAM; SSF48452; SSF48452; 1.
DR TIGRFAMs; TIGR00756; PPR; 5.
DR PROSITE; PS51375; PPR; 10.
PE 2: Evidence at transcript level;
KW Chloroplast; mRNA processing; Plastid; Reference proteome; Repeat;
KW Transit peptide.
FT TRANSIT 1..38
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 39..603
FT /note="Pentatricopeptide repeat-containing protein
FT At2g02980, chloroplastic"
FT /evidence="ECO:0000255"
FT /id="PRO_0000356005"
FT REPEAT 93..127
FT /note="PPR 1"
FT REPEAT 128..162
FT /note="PPR 2"
FT REPEAT 163..193
FT /note="PPR 3"
FT REPEAT 194..228
FT /note="PPR 4"
FT REPEAT 229..263
FT /note="PPR 5"
FT REPEAT 264..294
FT /note="PPR 6"
FT REPEAT 295..329
FT /note="PPR 7"
FT REPEAT 330..365
FT /note="PPR 8"
FT REPEAT 366..400
FT /note="PPR 9"
FT REPEAT 432..466
FT /note="PPR 10"
FT REGION 401..476
FT /note="Type E motif"
FT REGION 477..507
FT /note="Type E(+) motif"
FT REGION 508..603
FT /note="Type DYW motif"
SQ SEQUENCE 603 AA; 68170 MW; 6D3F09887CE1786A CRC64;
MAISSASLIS SFSHAETFTK HSKIDTVNTQ NPILLISKCN SLRELMQIQA YAIKSHIEDV
SFVAKLINFC TESPTESSMS YARHLFEAMS EPDIVIFNSM ARGYSRFTNP LEVFSLFVEI
LEDGILPDNY TFPSLLKACA VAKALEEGRQ LHCLSMKLGL DDNVYVCPTL INMYTECEDV
DSARCVFDRI VEPCVVCYNA MITGYARRNR PNEALSLFRE MQGKYLKPNE ITLLSVLSSC
ALLGSLDLGK WIHKYAKKHS FCKYVKVNTA LIDMFAKCGS LDDAVSIFEK MRYKDTQAWS
AMIVAYANHG KAEKSMLMFE RMRSENVQPD EITFLGLLNA CSHTGRVEEG RKYFSQMVSK
FGIVPSIKHY GSMVDLLSRA GNLEDAYEFI DKLPISPTPM LWRILLAACS SHNNLDLAEK
VSERIFELDD SHGGDYVILS NLYARNKKWE YVDSLRKVMK DRKAVKVPGC SSIEVNNVVH
EFFSGDGVKS ATTKLHRALD EMVKELKLSG YVPDTSMVVH ANMNDQEKEI TLRYHSEKLA
ITFGLLNTPP GTTIRVVKNL RVCRDCHNAA KLISLIFGRK VVLRDVQRFH HFEDGKCSCG
DFW
