PP146_ARATH
ID PP146_ARATH Reviewed; 689 AA.
AC Q9ZQ74;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Pentatricopeptide repeat-containing protein At2g03380, mitochondrial;
DE Flags: Precursor;
GN Name=PCMP-E47; OrderedLocusNames=At2g03380; ORFNames=T4M8.19;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=10809006; DOI=10.1023/a:1006352315928;
RA Aubourg S., Boudet N., Kreis M., Lecharny A.;
RT "In Arabidopsis thaliana, 1% of the genome codes for a novel protein family
RT unique to plants.";
RL Plant Mol. Biol. 42:603-613(2000).
RN [4]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the PPR family. PCMP-E subfamily. {ECO:0000305}.
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AC006284; AAD17437.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC05694.1; -; Genomic_DNA.
DR PIR; G84447; G84447.
DR RefSeq; NP_178437.1; NM_126389.2.
DR AlphaFoldDB; Q9ZQ74; -.
DR SMR; Q9ZQ74; -.
DR STRING; 3702.AT2G03380.1; -.
DR iPTMnet; Q9ZQ74; -.
DR PaxDb; Q9ZQ74; -.
DR PRIDE; Q9ZQ74; -.
DR ProteomicsDB; 250494; -.
DR EnsemblPlants; AT2G03380.1; AT2G03380.1; AT2G03380.
DR GeneID; 814867; -.
DR Gramene; AT2G03380.1; AT2G03380.1; AT2G03380.
DR KEGG; ath:AT2G03380; -.
DR Araport; AT2G03380; -.
DR TAIR; locus:2063771; AT2G03380.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_002706_0_6_1; -.
DR InParanoid; Q9ZQ74; -.
DR OMA; MYAKCHM; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; Q9ZQ74; -.
DR PRO; PR:Q9ZQ74; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZQ74; baseline and differential.
DR Genevisible; Q9ZQ74; AT.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; IDA:TAIR.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0009737; P:response to abscisic acid; IMP:TAIR.
DR GO; GO:0006979; P:response to oxidative stress; IMP:TAIR.
DR GO; GO:0009651; P:response to salt stress; IMP:TAIR.
DR GO; GO:0009451; P:RNA modification; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 5.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR045215; PPR_prot_plant.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR24015; PTHR24015; 1.
DR Pfam; PF01535; PPR; 5.
DR Pfam; PF13041; PPR_2; 4.
DR TIGRFAMs; TIGR00756; PPR; 7.
DR PROSITE; PS51375; PPR; 16.
PE 3: Inferred from homology;
KW Mitochondrion; Reference proteome; Repeat; Transit peptide.
FT TRANSIT 1..12
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 13..689
FT /note="Pentatricopeptide repeat-containing protein
FT At2g03380, mitochondrial"
FT /id="PRO_0000356006"
FT REPEAT 75..105
FT /note="PPR 1"
FT REPEAT 106..140
FT /note="PPR 2"
FT REPEAT 141..171
FT /note="PPR 3"
FT REPEAT 175..205
FT /note="PPR 4"
FT REPEAT 206..240
FT /note="PPR 5"
FT REPEAT 241..275
FT /note="PPR 6"
FT REPEAT 276..306
FT /note="PPR 7"
FT REPEAT 307..341
FT /note="PPR 8"
FT REPEAT 342..372
FT /note="PPR 9"
FT REPEAT 376..406
FT /note="PPR 10"
FT REPEAT 407..441
FT /note="PPR 11"
FT REPEAT 442..476
FT /note="PPR 12"
FT REPEAT 479..509
FT /note="PPR 13"
FT REPEAT 510..544
FT /note="PPR 14"
FT REPEAT 545..580
FT /note="PPR 15"
FT REPEAT 581..611
FT /note="PPR 16"
FT REGION 616..689
FT /note="Type E motif; degenerate"
SQ SEQUENCE 689 AA; 76685 MW; 2F581DB43F080343 CRC64;
MLRSITLSPT RRFGFPPRCV SFTTIKELIL TEENDGSSLH YAASSPCFLL LSKCTNIDSL
RQSHGVLTGN GLMGDISIAT KLVSLYGFFG YTKDARLVFD QIPEPDFYLW KVMLRCYCLN
KESVEVVKLY DLLMKHGFRY DDIVFSKALK ACTELQDLDN GKKIHCQLVK VPSFDNVVLT
GLLDMYAKCG EIKSAHKVFN DITLRNVVCW TSMIAGYVKN DLCEEGLVLF NRMRENNVLG
NEYTYGTLIM ACTKLSALHQ GKWFHGCLVK SGIELSSCLV TSLLDMYVKC GDISNARRVF
NEHSHVDLVM WTAMIVGYTH NGSVNEALSL FQKMKGVEIK PNCVTIASVL SGCGLIENLE
LGRSVHGLSI KVGIWDTNVA NALVHMYAKC YQNRDAKYVF EMESEKDIVA WNSIISGFSQ
NGSIHEALFL FHRMNSESVT PNGVTVASLF SACASLGSLA VGSSLHAYSV KLGFLASSSV
HVGTALLDFY AKCGDPQSAR LIFDTIEEKN TITWSAMIGG YGKQGDTIGS LELFEEMLKK
QQKPNESTFT SILSACGHTG MVNEGKKYFS SMYKDYNFTP STKHYTCMVD MLARAGELEQ
ALDIIEKMPI QPDVRCFGAF LHGCGMHSRF DLGEIVIKKM LDLHPDDASY YVLVSNLYAS
DGRWNQAKEV RNLMKQRGLS KIAGHSTME
