PP153_ARATH
ID PP153_ARATH Reviewed; 579 AA.
AC Q9ZQE5; Q94C14;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 2.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Pentatricopeptide repeat-containing protein At2g15690, mitochondrial;
DE Flags: Precursor;
GN Name=PCMP-H66; OrderedLocusNames=At2g15690; ORFNames=F9O13.24;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY.
RX PubMed=10809006; DOI=10.1023/a:1006352315928;
RA Aubourg S., Boudet N., Kreis M., Lecharny A.;
RT "In Arabidopsis thaliana, 1% of the genome codes for a novel protein family
RT unique to plants.";
RL Plant Mol. Biol. 42:603-613(2000).
RN [5]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND CLEAVAGE OF TRANSIT PEPTIDE AFTER
RP PHE-49.
RX PubMed=25732537; DOI=10.1093/jxb/erv064;
RA Carrie C., Venne A.S., Zahedi R.P., Soll J.;
RT "Identification of cleavage sites and substrate proteins for two
RT mitochondrial intermediate peptidases in Arabidopsis thaliana.";
RL J. Exp. Bot. 66:2691-2708(2015).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305|PubMed:25732537}.
CC -!- SIMILARITY: Belongs to the PPR family. PCMP-H subfamily. {ECO:0000305}.
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AC006248; AAD17413.2; -; Genomic_DNA.
DR EMBL; CP002685; AEC06430.1; -; Genomic_DNA.
DR EMBL; AY037247; AAK59848.1; -; mRNA.
DR EMBL; BT005808; AAO64743.1; -; mRNA.
DR PIR; B84532; B84532.
DR RefSeq; NP_565377.1; NM_127130.2.
DR AlphaFoldDB; Q9ZQE5; -.
DR SMR; Q9ZQE5; -.
DR BioGRID; 1421; 1.
DR IntAct; Q9ZQE5; 1.
DR STRING; 3702.AT2G15690.1; -.
DR iPTMnet; Q9ZQE5; -.
DR SwissPalm; Q9ZQE5; -.
DR PaxDb; Q9ZQE5; -.
DR PRIDE; Q9ZQE5; -.
DR ProteomicsDB; 249418; -.
DR EnsemblPlants; AT2G15690.1; AT2G15690.1; AT2G15690.
DR GeneID; 816062; -.
DR Gramene; AT2G15690.1; AT2G15690.1; AT2G15690.
DR KEGG; ath:AT2G15690; -.
DR Araport; AT2G15690; -.
DR TAIR; locus:2053659; AT2G15690.
DR eggNOG; KOG2521; Eukaryota.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_002706_45_1_1; -.
DR InParanoid; Q9ZQE5; -.
DR OMA; PHQWNQQ; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; Q9ZQE5; -.
DR PRO; PR:Q9ZQE5; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZQE5; baseline and differential.
DR Genevisible; Q9ZQE5; AT.
DR GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; IDA:TAIR.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR GO; GO:0009451; P:RNA modification; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR032867; DYW_dom.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR045215; PPR_prot_plant.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR24015; PTHR24015; 1.
DR Pfam; PF14432; DYW_deaminase; 1.
DR Pfam; PF13041; PPR_2; 1.
DR TIGRFAMs; TIGR00756; PPR; 1.
DR PROSITE; PS51375; PPR; 4.
PE 1: Evidence at protein level;
KW Mitochondrion; Reference proteome; Repeat; Transit peptide.
FT TRANSIT 1..49
FT /note="Mitochondrion"
FT /evidence="ECO:0000269|PubMed:25732537"
FT CHAIN 50..579
FT /note="Pentatricopeptide repeat-containing protein
FT At2g15690, mitochondrial"
FT /id="PRO_0000356013"
FT REPEAT 235..269
FT /note="PPR 1"
FT REPEAT 270..300
FT /note="PPR 2"
FT REPEAT 301..335
FT /note="PPR 3"
FT REPEAT 336..371
FT /note="PPR 4"
FT REPEAT 372..402
FT /note="PPR 5"
FT REGION 56..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 485..579
FT /note="Type DYW motif"
FT COMPBIAS 56..140
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..203
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 579 AA; 65614 MW; A9AFC1D28160B5E2 CRC64;
MSSLMAIRCA RTQNIVTIGS LLQLRSSFPR LSSQFHFSGT LNSIPIKHLS TSAAANDYHQ
NPQSGSPSQH QRPYPPQSFD SQNQTNTNQR VPQSPNQWST QHGGQIPQYG GQNPQHGGQR
PPYGGQNPQQ GGQMSQYGGH NPQHGGHRPQ YGGQRPQYGG PGNNYQNQNV QQSNQSQYYT
PQQQQQPQPP RSSNQSPNQM NEVAPPPSVE EVMRLCQRRL YKDAIELLDK GAMPDRECFV
LLFESCANLK SLEHSKKVHD HFLQSKFRGD PKLNNMVISM FGECSSITDA KRVFDHMVDK
DMDSWHLMMC AYSDNGMGDD ALHLFEEMTK HGLKPNEETF LTVFLACATV GGIEEAFLHF
DSMKNEHGIS PKTEHYLGVL GVLGKCGHLV EAEQYIRDLP FEPTADFWEA MRNYARLHGD
IDLEDYMEEL MVDVDPSKAV INKIPTPPPK SFKETNMVTS KSRILEFRNL TFYKDEAKEM
AAKKGVVYVP DTRFVLHDID QEAKEQALLY HSERLAIAYG IICTPPRKTL TIIKNLRVCG
DCHNFIKIMS KIIGRVLIVR DNKRFHHFKD GKCSCGDYW
